1,2-benzisothiazol-3(2H)-one 1,1-dioxide

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

5 mg/L

Assessment factor:

200

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

50 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.5 mg/L

Assessment factor:

2 000

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

50 mg/L

Assessment factor:

20

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

104.403 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

104.403 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

29.024 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

Classification is not triggered based on available data, according to REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006.

Conclusion on classification

Classification of 1,2-benzisothiazol-3(2H)-one 1,1-dioxide for effects in the environment

In determining the classification appropriate to 1,2-benzisothiazol-3(2H)-one 1,1-dioxide, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below. 

 

Persistence

Reliable studies are available to demonstrate that 1,2-benzisothiazol-3(2H)-one 1,1-dioxide is non persistent in nature and so is considered to have rapid biodegradation in the environment. In other words 1,2-benzisothiazol-3(2H)-one 1,1-dioxide degradation may therefore be expected to be fast. Thus it can be inferred that 1,2-benzisothiazol-3(2H)-one 1,1-dioxide is non persistent in character.  

 

Thus, 1,2-benzisothiazol-3(2H)-one 1,1-dioxide is not classified as a persistent (P) chemical. 

 

Potential to accumulate

The estimated log Kow values for 1,2-benzisothiazol-3(2H)-one 1,1-dioxide is less than 4 (Log Kow = 0.770). The potential for 1,2-benzisothiazol-3(2H)-one 1,1-dioxide to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 1000.  

 

The estimated BCF of 1,2-benzisothiazol-3(2H)-one 1,1-dioxide is highest 3.2 dimensionless and below the threshold of 2000. 

 

Thus, 1,2-benzisothiazol-3(2H)-one 1,1-dioxide does not satisfy the criterion for classification as bioaccumulative (B).

 

The toxicity values of fish, invertebrates and algae are LC50 = 293.411 mg/L, EC50 = 104.403 mg/L and NOEC = 16.266 mg/L, respectively. These values suggest classification for aquatic toxicity will not be applicable for all of the tropic levels and the same is based on the above mentioned estimation studies.

 

So,1,2-benzisothiazol-3(2H)-one 1,1-dioxidedoes not satisfy the environmental effects criterion for classification as toxic (T).

 

Thus it can be inferred that 1, 2-benzisothiazol-3(2H)-one 1,1-dioxide neither is P & B (including vPvB) substance, nor will qualify as T.