Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Two studies are available for acute oral toxicity: one in rats showing a combined oral LD50 equal to 3170 mg/kg bw with 95% confidence limits between 2260 and 4000 mg/kg bw, and one supporting study in mice showing an oral LD50 of 3600 mg/kg bw.
In an acute dermal toxicity study similar to OECD guideline 402, mortality was 0/5 male and 0/5 female at 2000 mg/kg bw and 4/5 males and 1/5 female at 5000 mg/kg bw.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
3 170 mg/kg bw

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

Two studies are available for acute oral toxicity: one in rats showing a combined oral LD50 equal to 3170 mg/kg bw with 95% confidence limits between 2260 and 4000 mg/kg bw, and one supporting study in mice showing an oral LD50 of 3600 mg/kg bw.

In an acute dermal toxicity study similar to OECD guideline 402, mortality was 0/5 male and 0/5 female at 2000 mg/kg bw and 4/5 males and 1/5 female at 5000 mg/kg bw.

Justification for classification or non-classification

LD50 in acute oral and dermal toxicity studies conducted similar to OECD guidelines were higher than 2000 mg/kg bw therefore the substance is not classified according to the Annex VI to the Directive 67/548/EEC and the CLP Regulation (EC) N° (1272-2008).