Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-857-7 | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The logKow of HMTBA was predicted by QSAR EPIWIN to be -0.07.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.07
Additional information
The solution of HMTBA is acidic; thus, the direct shake flask method (OECD 107) cannot be used, since HMTBA can to some extent form an ester with octanol: the esterification of octanol by HMTBA during shaking and phase separation cannot be excluded.
The presence of HMTBA in the organic phase would then result from a phenomenon other than mere solubility, thus rendering the test meaningless.
The HPLC test is likely to be made difficult to implement, because of the presence of at least four molecular species in the organic phase, with various elution times, making it difficult to determine a partition coefficient for monomer HMTBA.
The technical difficulties expected in the measurement of the octanol-water partition coefficient for HMTBA justify it to be evaluated by means of a QSAR
The logKow of HMTBA was predicted by QSAR EPIWIN to be -0.07.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
