Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-450-4 | CAS number: 65113-95-3
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 1985
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Report - Basic data given. No GLP guideline information given although conducted at a reputable laboratory which is GLP compliant facility.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 985
- Report date:
- 1985
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Deviations:
- not specified
- Principles of method if other than guideline:
- Report - Basic data given.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)pent-4-en-2-ol
- EC Number:
- 267-140-4
- EC Name:
- 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)pent-4-en-2-ol
- Cas Number:
- 67801-20-1
- IUPAC Name:
- 3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol
- Details on test material:
- - Super Sandalore (Ebanol)
- Batch number: C-51514
- Clear colourless liquid
- Stored in the dark under ambient conditions
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Details on test animals or test system and environmental conditions:
- No data included in the report.
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
- Amount / concentration applied:
- No data included in the report.
- Duration of treatment / exposure:
- Exposure period - 4 hours.
- Observation period:
- No data included in the report.
- Number of animals:
- No data included in the report.
- Details on study design:
- No data included in the report.
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- erythema score
- Basis:
- mean
- Time point:
- other: 0.5 hour
- Max. score:
- 2
- Reversibility:
- fully reversible within: 48 hours
- Remarks on result:
- other: n/a
- Irritation parameter:
- erythema score
- Basis:
- mean
- Time point:
- other: 24 Hour
- Max. score:
- 1
- Reversibility:
- fully reversible within: 48 hours
- Irritation parameter:
- erythema score
- Basis:
- mean
- Time point:
- other: 48 Hour
- Max. score:
- 0
- Reversibility:
- fully reversible within: 48 Hours
- Irritant / corrosive response data:
- Very slight to moderate irritant responses to Super Sandalore (Ebanol) were noted after a 4 hour exposure period. This was fully reversible within 48 hours.
Any other information on results incl. tables
Rabbit |
Erythema and Escher Formation |
Oedema Formation |
||||||||
No. |
Observation Time (h) |
Observation Time (h) |
||||||||
|
0.5 |
24 |
48 |
72 |
Mean Score |
0.5 |
24 |
48 |
72 |
Mean Score |
19 |
2 |
1 |
0 |
0 |
0.8 |
0 |
0 |
0 |
0 |
0 |
20 |
1 |
1 |
0 |
0 |
0.5 |
0 |
0 |
0 |
0 |
0 |
21 |
2 |
1 |
0 |
0 |
0.8 |
0 |
0 |
0 |
0 |
0 |
Applicant's summary and conclusion
- Interpretation of results:
- slightly irritating
- Remarks:
- Migrated information Fully reversible iwithin 48 hours. Criteria used for interpretation of results: not specified
- Conclusions:
- Ebanol is slightly irritating to rabbit skin, and fully reversible within 48 hours.
- Executive summary:
Very slight to moderate irritant responses to Super Sandalore (Ebanol) were noted after a 4 hour exposure period. This was fully reversible within 48 hours.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
