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Diss Factsheets
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EC number: 204-625-1 | CAS number: 123-41-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Auto flammability
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative self-ignition temperature (solids)
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is a solid having a melting point <= 160°C
- Endpoint:
- auto-ignition temperature (liquids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008-05-01 to 2008-06-02
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Well-documented GLP-study according Standard Test Method ASTM E659-78 (re-approved 2000).
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: ASTM E659-78 (re-approved 2000) Standard Test Method for Autoignition Temperature of Liquid Chemicals
- Deviations:
- no
- GLP compliance:
- yes
- Auto-ignition temperature:
- 380 °C
- Atm. press.:
- 101.4 kPa
- Remarks on result:
- other: No correction was required for barometric pressure. No cool flames were observed. A temperature rise of approximately 9 °C was observed at 297 °C, but no ignition.
- Conclusions:
- The present study was performed according Standard Test Method ASTM E659-78 (re-approved 2000) and compliant to GLP. So the study was assigned the reliability 1 and the results can be used to assess the physico-chemical hazards of Choline Base. The auto-ignition temperature was determined to be 380 °C at 101.4 kPa which indicates that the material is combustible at high temperatures.
- Executive summary:
The auto-ignition temperature of the test item was determined to be 380 °C at 101.4 kPa according to Standard Test Method ASTM E659-78 (re-approved 2000) and compliant to GLP.
Referenceopen allclose all
Hot flame autoignition temperature (AIT, °C) : 380
Time lag to auto-ignition (s) : 4
Barometric pressure (kPa) : 101.4
Sample quantity (μL) : 250
Cool Flame Observed down to (CFT, °C) : N/A
Reaction threshold temperature (RTT, °C) : 297
Table 1: Full Test results
Inner Flask Temp (°C) | Volume of Liquid (µL) | Clean Flask? yes (y) / no (n) | Ignition? yes (y) / no (n) | Time lag (s) | Comments |
500 | 100 | y | y | - | Small yellow flame |
400 | 100 | y | n | - | - |
440 | 100 | y | y | 1 | Small yellow flame |
425 | 100 | y | y | 4 | Small yellow flame |
419 | 100 | y | n | - | - |
422 | 100 | y | y | 3 | Small yellow flame |
419 | 200 | y | y | 2 | Small yellow flame |
413 | 200 | y | y | 4 | Small yellow flame |
409 | 200 | y | y | 2 | Large yellow flame |
400 | 200 | y | y | 4 | Large yellow flame |
391 | 200 | y | n | - | - |
394 | 200 | y | n | - | - |
397 | 300 | y | y | 4 | Small yellow flame |
394 | 300 | y | y | 3 | Medium yellow flame |
388 | 300 | y | n | - | - |
391 | 300 | y | n | - | - |
391 | 400 | y | y | 5 | Medium yellow flame |
388 | 400 | y | y | 3 | Small yellow flame |
383 | 400 | y | y | 4 | Medium yellow flame |
377 | 400 | y | n | - | - |
380 | 400 | y | n | - | - |
380 | 500 | y | n | - | - |
380 | 700 | y | n | - | - |
380 | 900 | y | n | - | - |
380 | 300 | y | n | - | - |
380 | 250 | y | y | 4 | Large yellow flame |
377 | 250 | y | n | - | - |
377 | 300 | y | n | - | - |
377 | 200 | y | n | - | - |
377 | 150 | y | n | - | - |
377 | 500 | y | n | - | - |
377 | 100 | y | n | - | - |
377 | 900 | y | n | - | - |
357 | 900 | y | n | - | - |
337 | 900 | y | n | - | - |
317 | 900 | y | n | - | - |
307 | 900 | y | n | - | - |
287 | 900 | y | n | - | No temp rise |
297 | 900 | y | n | - | 9°C rise (RTT) |
Description of key information
However, the auto-ignition temperature of a 45 % aqueous solution of choline hydroxide was determined to be 380 °C at 101.4 kPa.
Key value for chemical safety assessment
- Autoflammability / Self-ignition temperature at 101 325 Pa:
- 380 °C
Additional information
As supportive information handbook/collection data (Gestis, 2022) showed a self-ignition temperature of 430 °C for choline chloride, that is expected to have a similar flammability behaviour as pure choline hydroxide.
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