Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 947-618-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 C (Inherent Biodegradability: Modified MITI Test (II))
- Version / remarks:
- 1981, 00372 Version 1
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Date of receipt : 2014-07-18
Expiry date : 2016-01-07 - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Activated sludge from an aeration tank of two different wastewater treatment plants treating predominantly domestic wastewater (Wupper area water authority, WWTP Odenthal and WWTP Cologne-Stammheim).
Activated sludge from the aeration tanks of a wastewater treatment plant treating predominantly wastewater of industrial origin (WWTP Leverkusen Bürrig).
The three sludge types were mixed taking 2 parts from each of the two domestic WWTPS plus 1 part from the industrial WWTP.
Date of collections : 2015-08-17 - Duration of test (contact time):
- 28 d
- Initial conc.:
- 30 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Remarks:
- Consumption of oxygen (BOD) and chemical oxygen demand (COD)
- Details on study design:
- A measured volume of inoculated mineral medium, containing a known concentration of 30 mg/L of the test item was stirred in a closed flask at a constant temperature (25 ± 2 °C) under aerobic conditions in the dark.
The consumption of oxygen (BOD) was determined by measuring the drop in pressure in the automated respirometer flasks. Evolved carbon dioxide was absorbed in sodium hydroxide. The amount of oxygen taken up by the test item (corrected for uptake by blank inoculum, run in parallel) was expressed as a percentage of the chemical oxygen demand (COD).
The test lasted for 28 days.
The endogenous activity of the inoculum was checked running parallel blanks with inoculum but without test item. A reference compound (sodium benzoate) was run in parallel to check the operation of the procedures.
A toxicity control (test item and reference compound mixed, one replicate) was run in parallel, to ensure that the chosen concentration of the test item was not inhibitory to microorganisms.
Because of the nature of biodegradation and of the mixed bacterial populations used as inoculum, determinations of test item were carried out in quadruplicate, for the inoculum blank in triplicate and for the reference compound in duplicate.
The oxygen uptake was calculated from the readings taken at regular and frequent intervals, using the method given by the manufacturer of the equipment. At the end of incubation, the pH was measured in the flasks.
The degradation rate of the test item was set in relation to its experimentally determined COD. As the COD implicitly covers the oxygen demand for the nitrification process, there was no need to take additional correction measures into account.
Start of the incubation period : 2015-08-20
End of the incubation period : 2015-09-17 - Reference substance:
- benzoic acid, sodium salt
- Remarks:
- From Acros Organics, Purity: 99.9 %, Expiry date: 2018-03-27
- Parameter:
- % degradation (O2 consumption)
- Value:
- 14
- Sampling time:
- 7 d
- Remarks on result:
- other: Degradation mean from analysis in four flasks
- Parameter:
- % degradation (O2 consumption)
- Value:
- 19
- Sampling time:
- 14 d
- Remarks on result:
- other: Degradation mean from analysis in four flasks
- Parameter:
- % degradation (O2 consumption)
- Value:
- 23
- Sampling time:
- 21 d
- Remarks on result:
- other: Degradation mean from analysis in four flasks
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 23
- Sampling time:
- 28 d
- Remarks on result:
- other: Degradation mean from analysis in four flasks
- Key result
- Parameter:
- BOD5
- Value:
- 11.6 other: mg O2/L
- Remarks on result:
- other: blank-corrected mean BOD after 28d
- Parameter:
- COD
- Value:
- 1.651 other: mg O2/mg
- Remarks on result:
- other: Degradation of toxicity control, COD analytically determined
- Results with reference substance:
- The reference compound sodium benzoate showed 81 % degradation after 7 days and 82 % degradation after 14 days. Theoretical oxygen demand of reference compound (test concentration of 30 mg/L): 1.665 mg O2/mg.
- Validity criteria fulfilled:
- yes
- Remarks:
- The percent degradation of the reference compound sodium benzoate reached the level of ≥ 40 % after 7 days and ≥ 65 % after 14 days. No toxicity of the test item was observed in the toxicity control.
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- Within 28 days a degradation rate of 23 % was determined for EGGE 2806-1 and therefore EGGE 2806-1 is considered to be "Not Inherently Biodegradable".
- Executive summary:
This study was performed to assess the inherent biodegradability of EGGE 2806-1. The study was conducted in accordance with the OECD Guideline 302C “Inherent Biodegradability: Modified MITI Test (II)” (1981).
A suspension of EGGE 2806-1 in a mineral medium was inoculated with 40 % sludge of each of two different municipal sewage treatment plants (STP) and 20 % sludge of an industrial STP and incubated under aerobic conditions. During this period, degradation was followed by continuous automated BOD determinations.
EGGE 2806-1 showed:
14 % degradation after 7 days
19 % degradation after 14 days
23 % degradation after 21 days
23 % degradation after 28 days
Therefore, EGGE 2806-1 is considered to be “Not Inherently Biodegradable”.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- Adopted July 1992, 00090 Version 1
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Version / remarks:
- 2008
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Date of receipt : 2014-07-18
Expiry date : 2015-07-12 - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Origin : aeration tank of a wastewater plant treating predominantly domestic sewage (Wupper area water authority, WWTP Odenthal)
Date of collection : 2015-05-18
Concentration of inoculum : 30 mg/L suspended solids - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Remarks:
- Consumption of oxygen (BOD) and chemical oxygen demand (COD)
- Details on study design:
- A suspension of 100 mg/L test item in a mineral medium, equalling to 50-100 mg ThOD or COD/Litre as the nominal sole source of organic carbon, was stirred in a closed flask and inoculated at a constant temperature (22 ± 1 °C) for up to 28 days under aerobic conditions in the dark.
The consumption of oxygen (BOD) was determined by measuring the drop in pressure in the automated respirometer flasks. Evolved carbon dioxide was absorbed in sodium hydroxide. The amount of oxygen taken up by the test item (corrected for uptake by blank inoculum, run in parallel) was expressed as a percentage of chemical oxygen demand (COD).
The endogenous activity of the inoculum was checked running parallel blanks with inoculum but without test item. A reference compound (sodium benzoate) was run in parallel to check the operation of the procedures.
A toxicity control (test item and reference compound mixed, one replicate) was run in parallel, to ensure that the chosen concentration of the test item was not inhibitory to microorganisms.
Degradation was followed by the determination of oxygen uptake and measurements were taken at frequent intervals to allow the identification of the beginning and end of biodegradation and the slope of the biodegradation curve.
The test lasted for 28 days.
Because of the nature of biodegradation and of the mixed bacterial populations used as inoculum, determinations of test item and inoculum blank were carried out in triplicate and of reference compound in duplicate.
The oxygen uptake was calculated from the readings taken at regular and frequent intervals, using the method given by the manufacturer of the equipment. At the end of incubation, the pH was measured in the flasks.
The degradation rate of the test item was set in relation to its experimentally determined COD. As the COD implicitly covers the oxygen demand for the nitrification process, there was no need to take additional correction measures into account.
Start of the incubation period : 2015-05-20
End of the incubation period : 2015-06-17 - Reference substance:
- benzoic acid, sodium salt
- Remarks:
- from Acros Organics, Purity: 99.9 %, Expiry date: 2018-03-27
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1
- Sampling time:
- 7 d
- Remarks on result:
- other: Degradation mean from analysis in three flasks
- Parameter:
- % degradation (O2 consumption)
- Value:
- 10
- Sampling time:
- 14 d
- Remarks on result:
- other: Degradation mean from analysis in three flasks
- Parameter:
- % degradation (O2 consumption)
- Value:
- 16
- Sampling time:
- 21 d
- Remarks on result:
- other: Degradation mean from analysis in three flasks
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 18
- Sampling time:
- 28 d
- Remarks on result:
- other: Degradation mean from analysis in three flasks
- Key result
- Parameter:
- BOD5
- Value:
- 29 other: mg O2/L
- Remarks on result:
- other: blank-corrected mean BOD after 28d
- Parameter:
- COD
- Value:
- 1.651 other: mg O2/mg
- Remarks on result:
- other: Degradation of test item, COD analytically determined
- Results with reference substance:
- The reference compound sodium benzoate showed 87 % degradation after 14 days.
- Validity criteria fulfilled:
- yes
- Remarks:
- All validity criteria of the test method were met
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- Within 28 days, a degradation rate of 18 % was determined for EGGE 2806-1. EGGE 2806-1 is considered to be "Not Readily Biodegradable".
- Executive summary:
This study was performed to assess the ready biodegradability of EGGE 2806-1. It was conducted in accordance with the Council Regulation (EC) No 440/2008, Method C.4-D “Manometric Respirometry Test“(2008). This test method is in all essential parts identical with OECD Guideline 301 F (adopted July 1992).
A suspension of EGGE 2806-1 in a mineral medium was inoculated and incubated for 28 d under aerobic conditions. During this period, degradation was followed by continuous automated BOD determinations.
EGGE 2806-1 showed:
1 % degradation after 7 days
10 % degradation after 14 days
16 % degradation after 21 days
18 % degradation after 28 days
Therefore, EGGE 2806-1 is considered to be “Not Readily Biodegradable“.
Referenceopen allclose all
All validity criteria of the test method were met:
The reference compound reached the level of ≥ 60 percent for ready biodegradability within 14 days.
The toxicity control exhibited degradation rates > 25 % within 14 days.
At the end of the test, at the plateau, or the end of the 10-d window, biodegradation in parallels with test item did not differ by more than 20 percentage points.
The oxygen uptake of the inoculum blank was ≤ 60 mg/L.
In cases where the degradation was ≤ 60 %, the pH values were in between 6.0 and 8.5 at the end of the test.
Description of key information
A study was performed to assess the inherent biodegradability of EGGE 2806-1. The study was conducted in accordance with the OECD Guideline 302C “Inherent Biodegradability: Modified MITI Test (II)” (1981).
EGGE 2806-1 showed 23 % degradation after 28 days and is therefore considered to be “Not Inherently Biodegradable”.
A further study was performed to assess the ready biodegradability of EGGE 2806-1. The study was conducted in accordance with the Council Regulation (EC) No 440/2008, Method C.4-D “Manometric Respirometry Test“(2008). This test method is in all essential parts identical with OECD Guideline 301 F (adopted July 1992).
EGGE 2806-1 showed 18 % degradation after 28 days and is therefore considered to be “Not Readily Biodegradable“.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.