Registration Dossier
Registration Dossier
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EC number: 301-037-8 | CAS number: 93980-59-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15 - 17 Nov 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- GLP compliance:
- yes
- Type of method:
- column elution method
- Key result
- Water solubility:
- < 0.525 mg/L
- Temp.:
- 20 °C
- pH:
- 5.9
Reference
Test results
Flow rate |
pH |
Concentration of test item in test solution (mg/L) |
|
Measurement value |
Average |
||
0.4 mL/min |
5.9 |
< 0.525 |
< 0.525 |
5.9 |
< 0.525 |
||
Water solubility of test item: < 0.525 mg/L (20 °C)
Discussion
The test item was hardly soluble in water and the water solubility was less than the concentration calculated from the limit of quantification. However, the analytical method was judged to be valid because acceptable recovery rate (the average recovery rate: 95.3%) was obtained in the recovery test. Therefore, it was concluded that the test results were acceptable.
Description of key information
Water solubility < 0.525 mg/L at 20 °C, pH 5.9 (OECD Guideline 105, column elution method)
Key value for chemical safety assessment
Additional information
The test item was hardly soluble in water and the water solubility was less than the concentration calculated from the limit of quantification. However, the analytical method was judged to be valid because acceptable recovery rate (the average recovery rate: 95.3%) was obtained in the recovery test. Therefore, it was concluded that the test results were acceptable.
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