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EC number: 224-623-4 | CAS number: 4430-31-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Abiotic degradation:
Air: Based on estimation with the QSAR model Aopwin the substance undergoes in air rapid degradation after reaction with hydroxyl radicals. The DT50 value after reaction with hydroxyl radicals is 8.2 hours. The substance will not reach the stratosphere and is therefore not considered to be a long-range transported chemical in air.
The substance does not have an ozone depletion potential because it does not contain halogens and does not have the potential to reach the stratosphere (GHS, 6th Edition, CLP, 2008).
Water: The rate of hydrolysis of the substance at pH values normally found in the environment (pH 4-9) was determined in a GLP-compliant study according to OECD 111. The half-life time of the substance at 25°C and pH 4, pH 7 and pH 9 was determined to be > 1 year, 17 days and 8.4 hours, respectively. The substance is anticipated to be hydrolysed in the lactone ring forming a monocyclic secondary alcohol on one end and an acid at the other end.
Biotic degradation:
In a biodegradation screening study (OECD TG 301D), after 28 days exposure of river water to 2 mg/L substance, 71% biodegradation was observed. Based on these findings the substance is considered to be readily biodegradable.
Bioaccumulation:
Aquatic and terrestrial organisms: Based on the log Kow it can be concluded that the substance has no bioaccumulation potential with calculated BCF values for aquatic and terrestrial organisms of 3.09 and 1.14 L/kg ww, respectively.
Transport and distribution:
The adsorption/desorption screening study was not conducted as the substance has a low octanol water partition coefficient. For the CSA, the Koc is therefore calculated. Using the measured log Kow (1.4) and the default QSAR used in EUSES - Koc = 10.47*(Kow)^0.52 - the Koc is calculated to be 56 L/kg and the log Koc 1.75. Based on this value it may be concluded that the substance has low potential for adsorption to solid surfaces.
A Henry's law constant of 4.1E-4 Pa·m³/mol (at 12 °C) was calculated in EUSES (Vap pressure 0.21 Pa at 24°C, 154.21 molecular weight and 39953 mg/l at 24°C water solubility). Based on this value the substance will not partition from water to air.
Based on Level III environmental distribution modelling using EPISUITE (assuming equal and continuous releases to air, water and soil) using the CAS number 4430-31-3, it is estimated that the majority of the substance released to the environment will partition mainly into soil (71.6%) and water (26.6%) with small amounts to air (1.63%) and sediment (0.18%).
The SimpleTreat model, which is incorporated in EUSES, simulates the distribution of the substance in a Sewage Treatment Plant (STP). Model calculations show that 86.9% of the substance will be degraded and that 1.7E-4 %, 12.6% and 0.525% will partition to air, water and sewage sludge, respectively.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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