Registration Dossier
Registration Dossier
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EC number: 255-925-4 | CAS number: 42739-64-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to aquatic invertebrates
Key value for chemical safety assessment
Additional information
There are no studies available that assess the acute toxicity of the test substance to aquatic invertebrates. However, as the test substance belongs to the substance category of Phthalocyanines whose category members resemble in their chemical structure as well as in their phys-chem properties, a read-across approach was used to cover this endpoint.
The toxicity of Phthalocyanines to Daphnia magna was tested by several guideline studies conducted with the analogue substances CAS 59160-79-1, CAS 147-14-8 and CAS 1328-53-6.
The toxicity of CAS 59160 -79 -1 to the freshwater invertebrate Daphnia magna was assessed in a study following OECD 202 with static test design and analytical monitoring. An EC50 > 100 mg/L was identified in this study after 48 h of exposure [Ibacon 2015].
The toxicity of CAS 147-14-8 to Daphnia magna was tested in a study following EU Directive 79/831/EEC. The animals were exposed to the test substance for 48 hours and an EC50 > 500 mg/l was determined [BASF AG 1989]. However, a solubilizer was used in this test. Nevertheless, the result is supported by two further studies conducted with CAS 147-14-8 in accordance with EEC Directive 93/32/EEC. In both studies an EC50 (48h) >100 mg/l was determined [BASF AG 2001, 2004].
The results of a study conducted with CAS 1328-53-6 is comparable to the data obtained from testing with CAS 147-14-8. The toxic effect of the substance on D. magna was investigated in a study following directive 84/449/EEC, C.2. The test substance was dissolved in the test water by using a solubilizer. After 48 hours the test was terminated and an EC50 (48h) of > 500 mg/l was determined [BASF AG 1988].
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