Registration Dossier
Registration Dossier
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EC number: 255-925-4 | CAS number: 42739-64-0
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to fish.
Key value for chemical safety assessment
Additional information
There are no studies available that assess the acute toxicity of the test substance to fish. However, as the test substance belongs to the substance category of Phthalocyanines whose category members resemble in their chemical structure as well as in their phys-chem properties, a read-across approach was used to cover this endpoint.
A study on the toxicity of CAS 59160-79-1 to fish revealed no toxicity to fish (LC50 > 10000 mg/L) at test determination after 96h. This test was run in a static system according to OECD 203 with analytical monitoring [BASF 1999].
Several studies on the toxicity of CAS 147-14-8 to fish detected no lethal effects. All tests were run without analytical monitoring. A screening study performed in a static system with Brachydanio rerio according to OECD 203 determined a LC50 >100 mg/l at test termination after 96 h in [BASF AG 2004]. The result is supported by another study in whichOryzias latipeswas exposed to the substance in a following Japanese guideline JIS K 0102-1986-71. After 48 hours of exposure a LC50 >100 mg/l was determined [MITI 1992]. Comparable results were obtained by a test accomplished in compliance with German standard DIN 38412 part L15 using a solubiliser. The study was performed using static test system withLeuciscus idusas test organism. The test was terminated after 96 hours and a LC50 > 2200 mg/l was determined [BASF AG 1978]. In a second static test following German standard DIN 38412 part L15 without solubiliser a LC50 (96 h) of 3200 mg/l was determined [BASF AG 1978]. A third test performed in compliance with German standard DIN 38412 part L15 a LC50 of ca. 46 mg/l was determined inLeuciscus idus[BASF AG 1991]. However, the test substance contained water soluble impurities that probably caused the toxic effects.
Acute toxicity testing with a third substance of the category (CAS 1328-53-6) showed similar results. A 48 hour static study conducted with Oryzias latipes in compliance with guideline JIS K 0102 -1986 -71 detected a LC50 (96h) > 250 mg/L [MITI 1992].
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