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EC number: 255-255-2 | CAS number: 41198-08-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study performed according to OECD Guidelines
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate
- EC Number:
- 255-255-2
- EC Name:
- O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate
- Cas Number:
- 41198-08-7
- Molecular formula:
- C11H15BrClO3PS
- IUPAC Name:
- 4-bromo-2-chlorophenyl ethyl (propylsulfanyl)phosphonate
- Test material form:
- liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test substrate
- Details on preparation and application of test substrate:
- - Method of mixing into soil: Stock solution was mixed with 100 g of fine sand. The hexane solvent was evaporated overnight at room temperature. The dry stock mixtures were then mixed with dry premixed artificial soil in a Hobart blender. Water was then added to the blend. - Method of application to soil surface (if used):- Controls: Water and vehicle controls performed- Chemical name of vehicle: Hexane- Evaporation of vehicle before use: Yes.
Test organisms
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Details on test organisms:
- TEST ORGANISM- Common name: Earthworm- Source: De T. Wilde, Farm Research, D-7867 Wehr/Baden, Germany- Age at test initiation: > 2 months - Weight at test initiation: 278-370 mgACCLIMATION- Acclimation period: 24 hr- Acclimation conditions: 24 hr conditioning in soil used for the test
Study design
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Total exposure duration:
- 14 d
Test conditions
- Test temperature:
- 22°C ± 2 °C
- pH:
- 5.5-6.2
- Moisture:
- 24-38%
- Details on test conditions:
- TEST SYSTEM- Test container: Beakers of 1L filled with 750g soil (wet weight), covered with watch glasses- No. of organisms per container (treatment): 10- No. of replicates per treatment group:4- No. of replicates per control: 4- No. of replicates per vehicle control: 4OTHER TEST CONDITIONS- Photoperiod: Continuous illumination - Light intensity: 400/800 Lux cold white fluorescent light.VEHICLE CONTROL PERFORMED: yes
- Nominal and measured concentrations:
- Nominal concentrations:0, 12.3, 37.0, 111, 333 and 1000 mg/kg dry weight soil.
Results and discussion
Effect concentrations
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- 372 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: 95% CL 298-463 mg/kg dw
Any other information on results incl. tables
Details on mortality levels observed are given in the table below.
Nominal concentration (mg/kg dry weight of soil) |
Dead organisms after (cumulated data n=40) |
||
7 days |
14 days |
% after 14 days |
|
Blank |
0 |
0 |
- |
Vehicle |
0 |
0 |
- |
12.3 |
0 |
0 |
- |
37.0 |
0 |
1 |
2.5 |
111 |
0 |
5 |
12.5 |
333 |
0 |
12 |
30 |
1000 |
0 |
38 |
95 |
The average weights of worms at the start and the end of the exposure period are given in the following table.
Nominal concentration (mg/kg dry weight of soil) |
Average live weight of test organisms (mg) |
|
Start of exposure |
End of exposure |
|
Blank |
278 |
271 |
Vehicle |
370 |
244 |
12.3 |
297 |
232 |
37.0 |
288 |
216 |
111 |
310 |
241 |
333 |
305 |
194 |
1000 |
293 |
190 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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