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Diss Factsheets
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EC number: 201-058-1 | CAS number: 77-78-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 14 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 3.8 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- sensitivity distribution
Hazard for air
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 2 µg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Additional information
No analytical determination was performed in any of the freshwater acute ecotoxicity studies. Therefore, in all cases the values based on the nominal concentration.
Another note must be made: DMS hydrolyses very fast (DT50 <1d) in water to monomethyl sulfate and methanol. Therefore, the toxicity/immobilisation and inhibition, respectively observed is predominantly based on the hydrolysis product monomethyl sulfate. This approach is conform to the guidance OECD series 23 (2000).
It could be excluded that the ecotoxicity effects observed are due to methanol (96 h LC50 fish: 19,000 mg/l; 24 h EC50 daphnids: >10,000 mg/l; EC50 algae: 36,000 mg/l, ECETOC, 1996) and therefore it can be concluded that the toxicity can mainly be attributed to DMS and methyl sulphate.
According to the EU RAR (2002); similarly to the PNECwater and the PNECmicroorganisms is based on the toxicity of DMS and its
hydrolysis products. However, due to the short exposure period (3 hours) in the activated sludge test the fraction of DMS will probably be higher than that in the aquatic tests (48-96 hours).
Conclusion on classification
The substance DMS has the following endpoint specific parameter which should be used to classify the substance:
96 hr LC50 (for fish): 14 mg/L
48 hr EC50 (for crustacea): 17 mg/L
72 hr ErC50 (for algae): 46.9 mg/L
Due to the results given above, the most sensitive species is the golden orfe with an LC50 (96h) of 14 mg/L.
Furthermore, in a screening test the substance was tested to be readily biodegradable. Therefore, and in accordance to regulation (EC) No.: 1272/2008 the substance does not have to classify as dangerous for the environment.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.