Registration Dossier
Registration Dossier
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EC number: 619-764-7 | CAS number: 173904-11-5
Endpoint summary
Administrative data
Description of key information
Additional information
Hydrolysis:
The hydrolysis of Incorez 397 in different aqueous buffer solutions (pH = 4, 7 and 9) at room temperature (25 °C) was investigated using LC/MS and MS/MS. After 5 minutes hydrolysis under these conditions Incorez 397 could not be detected (t1/2 < 5 minutes). It could be shown that the hydrolysis of Incorez 397 was independent from the pH of the aqueous media. The degradation products (1,3-cyclohexanebis (methylamine) and isobutyraldehyde) were successfully identified using reference spectra. Recovery data showed that 1,3-cyclohexanebis(methylamine) was quantitatively formed from Incorez 397 in different aqueous buffer solutions (pH = 4, 7, 9).The storage stability of 1,3-Cyclohexanebis(methylamine) in different buffer solutions (pH = 4, 7 and 9) at room temperature was determined to be at least 5 days.
Biodegradation:
Incorez 397 was assessed in a closed bottle test in accordance to OECD guideline 301 D and EU method C.4 VI. The test item was exposed to activated sludge from an aeration tank for 28 days. Under the test conditions the percentage biodegradation of Incorez 397 reached a mean of 5.9 % based on ThODNO3. Thus, Incorez 397 was not ready biodegradable.
Transport and distribution:
The test method for the determination of the adsorption coefficient (Koc) of a substance as described for liquid materials in test guideline C.19 of EC Regulation 440/2008 was replaced by a theory based evaluation. Due to the fast and spontaneous hydrolysis of Incorez 397 upon contact with water, experimental determination of the Koc was technically not feasible. The log Koc of Incorez 397 was calculated using the US EPA EPIWIN (v4.0) software. The resulting log Koc was 5.13.
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