Registration Dossier
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EC number: 444-370-5 | CAS number: 669005-94-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The test item is with high probability acutely not harmful to aquatic invertebrates. No acute toxic effects occur on Daphnia magna up to the solubility limit in test water under the present test conditions.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
The acute toxicity of the test item to Daphnia magna was determined in a 48-hour static test according to the EU Commission Directive 92/69/EEC, Part C.2 (1992), and the OECD Guideline for Testing of Chemicals, No. 202, Part I (1984) (RCC Ltd. 2003c).
Due to the low water solubility of the test item, a supersaturated dispersion of the test item with a loading rate of 100 mg/L was continuously stirred at room temperature in the dark for 96 hours. Then the dispersion was filtered (0.45 µm). Only the undiluted filtrate with the maximum concentration of dissolved test item was used as test medium. Additionally, a control was tested in parallel. Thus a limit test was performed according to the EU Commission Directive 92/69/EEC.
In the control and in the undiluted filtrate (loading rate of 100 mg/L) no immobilized test organisms or other signs of intoxication were determined during the test period of 48 hours.
The analytically determined test item concentration in the analyzed test medium samples of the undiluted filtrate amounted to 0.0016 mg/L at the start of the test, and was below the limit of detection of the analytical method (LOD = 0.05 pg/L) at the end of the test. The biological results are based on the loading rate of 100 mg/L.
The 48-hour NOEC (highest concentration tested without toxic effects after the exposure period of 48 hours) and the 48-hour ECO of the test item to Daphnia magna were determined to be at least at a loading rate of 100 mg/L. The 48-hour NOEC and the 48 hour ECO might even be higher, but concentrations in excess of the loading rate of 100 mg/L have not been tested due to the limited water solubility of the test item in the test water. The 48-hour EC50 and the 48-hour EC100 were clearly higher than the loading rate of 100 mg/L.
The test item had no acute toxic effects on Daphnia magna up to the solubility limit in test water under the present test conditions.
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