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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 7 November - 14 November 2022
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Justification for type of information:
- Non-GLP study; suitable for registration and classification.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- not specified
- GLP compliance:
- no
- Type of method:
- effusion method: Knudsen cell
- Specific details on test material used for the study:
- No further details in the study report
- Key result
- Test no.:
- #1
- Temp.:
- 296.85 K
- Vapour pressure:
- >= 0.081 - <= 0.084 Pa
- Key result
- Test no.:
- #2
- Temp.:
- 300.15 K
- Vapour pressure:
- >= 0.07 - <= 0.073 Pa
- Key result
- Test no.:
- #3
- Temp.:
- 307.05 K
- Vapour pressure:
- >= 0.082 - <= 0.086 Pa
- Key result
- Test no.:
- #4
- Temp.:
- 314.15 K
- Vapour pressure:
- >= 0.011 - <= 0.012 Pa
- Key result
- Test no.:
- #5
- Temp.:
- 321.65 K
- Vapour pressure:
- >= 0.045 - <= 0.047 Pa
- Conclusions:
- In conclusion, the vapour pressure of RED HF2 is below 0.29 Pa at 48.4°C and therefore the vapour pressure of RED HF2 at 20°C and 25°C is below 0.29 Pa.
- Executive summary:
The vapour pressure of RED HF2 was measured using the Knudsen effusion method as described in EU method A.4 and OECD 104.
In this method, the mass of the test substance flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions was determined at various specified temperatures (from 23.8°C to 48.4°C). However, the mass loss observed was of the same order of magnitude as the baseline mass variation. As the test item started to spread from the lid hole, no new test with higher temperatures was performed.
The Hertz-Knudsen equation was still used to calculate the vapour pressure corresponding to the observed mass loss rate.
The Log10 (Vapour Pressure (Pa)) was plotted against 1/T (K) but no linear function was obtained and therefore no vapour pressure can be calculated by extrapolating these results.
Considering the accuracy of the TG-DSC integrated balance (50 µg), no significant mass-loss was observed along the measurements even with the highest temperature (48.4°C).
Therefore an upper value of vapour pressure can be given considering the precision of the balance:
Using the Hertz-Knudsen formula with the highest temperature (48.4°C) and a mass-loss corresponding to the precision of the balance (0.05 mg) gives a vapour pressure of 0.29 Pa. The pressures calculated from the thermograms are thus of the same order of magnitude as the pressure obtained using the precision of the balance.
In conclusion, the vapour pressure of RED HF2 is below 0.29 Pa at 48.4°C and therefore the vapour pressure of RED HF2 at 20°C and 25°C is below 0.29 Pa.
Reference
Table 2. Experimental Results
Mass loss (mg) | Mass loss duration (s) | Vapour pressure (Pa)* | Log10 (p)* | Temperature (K) | 1/T (1/K) |
0.015 | 600 | 0.0808 ; 0.0843 | -1.0924 ; -1.0741 | 296.85 | 3.369 x 10-3 |
0.013 | 600 | 0.0705 ; 0.0735 | -1.1520 ; -1.1337 | 300.15 | 3.332 x 10-3 |
0.015 | 600 | 0.0822 ; 0.0858 | -1.0850 ; -1.0667 | 307.05 | 3.257 x 10-3 |
0.002 | 600 | 0.0111 ; 0.0116 | -1.9549 ; -1.9366 | 314.15 | 3.183 x 10-3 |
0.008 | 600 | 0.0449 ; 0.0468 | -1.3481 ; -1.3298 | 321.65 | 3.109 x 10-3 |
*: lowest and highest values calculated depending on molar mass value used.
Description of key information
In conclusion, the vapour pressure of RED HF2 is below 0.29 Pa at 48.4°C and therefore the vapour pressure of RED HF2 at 20°C and 25°C is below 0.29 Pa.
Key value for chemical safety assessment
- Vapour pressure:
- 0.29 Pa
- at the temperature of:
- 48.4 °C
Additional information
In this method, the mass of the test substance flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions was determined at various specified temperatures (from 23.8°C to 48.4°C). However, the mass loss observed was of the same order of magnitude as the baseline mass variation. As the test item started to spread from the lid hole, no new test with higher temperatures was performed.
The Hertz-Knudsen equation was still used to calculate the vapour pressure corresponding to the observed mass loss rate.
The Log10 (Vapour Pressure (Pa)) was plotted against 1/T (K) but no linear function was obtained and therefore no vapour pressure can be calculated by extrapolating these results.
Considering the accuracy of the TG-DSC integrated balance (50 µg), no significant mass-loss was observed along the measurements even with the highest temperature (48.4°C).
Therefore an upper value of vapour pressure can be given considering the precision of the balance:
Using the Hertz-Knudsen formula with the highest temperature (48.4°C) and a mass-loss corresponding to the precision of the balance (0.05 mg) gives a vapour pressure of 0.29 Pa. The pressures calculated from the thermograms are thus of the same order of magnitude as the pressure obtained using the precision of the balance.
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