Registration Dossier
Registration Dossier
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EC number: 245-740-7 | CAS number: 23564-05-8
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 1992-03-19 to 1992-04-10
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
- Key result
- Water solubility:
- 40 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 50 g/L
- Incubation duration:
- >= 1 - <= 2 h
- Temp.:
- 25 °C
- Remarks on result:
- other: pH not reported
- Conclusions:
- The water solubility was determined to be 40 mg/L at 25 °C.
- Executive summary:
A study was conducted equivalent to OECD Test Guideline 105 (1995) using the Flask method. The test item was put into a flask and water was added. Samples were taken after 1 h and 2 h of stirring, respectively. The water solubility was determined to be 40 mg/L at 25 °C.
Reference
In case of stirring for 1 hour, sample weight and its concentration of test item by HPLC analysis were as follows:
1. 9983.8 mg
2. 10726.3 mg
In case of stirring for 2 hour, sample weight and its concentration of test item by HPLC analysis were as follows:
1. 9524.3 mg
2. 9041.2 mg
The water solubility was determined to be 40 mg/L at 25 °C.
Description of key information
The water solubility was determined to be 40 mg/L at 25 °C.
Key value for chemical safety assessment
- Water solubility:
- 40 mg/L
- at the temperature of:
- 25 °C
Additional information
A study was conducted equivalent to OECD Test Guideline 105 (1995) using the Flask method. The test item was put into a flask and water was added. Samples were taken after 1 h and 2 h of stirring, respectively. The water solubility was determined to be 40 mg/L at 25 °C.
Furthermore, two older studies are available for the determination of the water solubility of the test item. In a study from 1986 according to OECD Test Guidelines 1981 the water solubility was determined by the flask method to be 21.8 mg/L at 25 °C.
In another study from 1987 according to EPA Guideline CG-1500 the water solubility was determined to be 24.6 mg/L at 25 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
