Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 948-046-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- Reaction mass of benzenamine, 2-ethyl-N-(2-ethyl-nonylphenyl) nonyl-, branched and benzenamine, 2-ethyl-N-(2-ethyl-nonylphenyl)-, branched
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- Reaction mass of benzenamine, 2-ethyl-N-(2-ethyl-nonylphenyl) nonyl-, branched and benzenamine, 2-ethyl-N-(2-ethyl-nonylphenyl)-, branched
- Reference substance:
- Reaction mass of benzenamine, 2-ethyl-N-(2-ethyl-nonylphenyl) nonyl-, branched and benzenamine, 2-ethyl-N-(2-ethyl-nonylphenyl)-, branched
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The substance is a substance of Unknown or Variable composition, Complex reaction products or Biological materials (UVCB) with multiple constituents. The physical state of the substance, reaction mass of benzenamine, 2-ethyl-n-(2-ethyl-nonylphenyl)nonyl-, branched and benzenamine, 2-ethyl-n-(2-ethyl-nonylphenyl)-, branched, is a dark amber liquid at room temperature and therefore, potential inhalation of the substance is negligible.
The two main constituents are benzenamine, 2-ethyl-n-(2-ethyl-nonylphenyl) nonyl-, branched and benzenamine, 2-ethyl-n-(2-ethyl-nonylphenyl)-, branched and their concentrations are typically 48% and 43%, respectively. The water solubility of the two main constituents are < 0.00076 mg/L and < 0.00027mg/L at 20 °C and pH 7, respectively. The partition coefficients (Log Kow) of the two main constituents are > 9.6 and > 9.1 at pH 7, respectively. The typical molecular masses of the two main constituents (C34H55N and C25H37N) are 477.82 and 351.56 Daltons, respectively. These data indicate that the substance has extremely low water solubility (< 0.1 mg/L) and is a highly lipophilic (Log Pow > 5.6) molecule, and thus the substance is not bioavailable via the oral route in accordance with Lipinski's rule of five. In addition, acute oral toxicity study in rats did not show any systemic effects up to 2000 mg/kg, the highest doses tested. Repeated dose oral toxicity studies in rats did not show any systemic effects up to 1000 mg/kg/day, the highest doses tested in both 14-day oral toxicity study and combined repeated dose oral toxicity study with the reproductive/developmental toxicity screening test. No information is currently available on possible degradation products produced in the gastrointestinal tract.
The extremely low water solubility and high lipophilicity of the substance also indicate that it is not expected to be absorbed via the dermal route. The local lymph node assay (LLNA) in mouse showed that the substance is not a skin sensitizer.
Additionally, the ready biodegradability test of the substance showed that it was 0% biodegradation after 28 days and was not considered readily biodegradable. The measured test concentrations of the substance in aquatic medium were very low, less than 0.344 mg/L in the acute toxicity tests in aquatic organisms (algae, daphnia, and fish). The substance is therefore expected to have low potential for bioaccumulation in aquatic organisms although the substance is persistent and its Log Pow exceeds 5.
In conclusion, based upon the available data, bioavailability of the substance, reaction mass of benzenamine, 2-ethyl-n-(2-ethyl-nonylphenyl)nonyl-, branched and benzenamine, 2-ethyl-n-(2-ethyl-nonylphenyl)-, branched,is expected to be very limited and the substance has low systemic toxicity.
Reference
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.