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EC number: 810-288-7 | CAS number: 1700656-13-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: simulation testing on ultimate degradation in surface water
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is readily biodegradable
- Endpoint:
- biodegradation in water: sediment simulation testing
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is readily biodegradable
- Endpoint:
- biodegradation in water: sewage treatment simulation testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- September 2015
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 303 A (Simulation Test - Aerobic Sewage Treatment. A: Activated Sludge Units)
- Version / remarks:
- Only Preliminary test was done
- GLP compliance:
- no
- Remarks:
- only Preliminary test
- Radiolabelling:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Reasons for the selection of the study system
Activated sludge from the sewage plant at Hildesheim is well suited as it comprises mostly municipal sewage and hardly industrial chemical waste.
Source
Municipal sewage treatment plant, D-31137 Hildesheim
Pretreatment
The activated sludge was washed with chlorine free tap water, concentrated and afterwards maintained in an aerobic condition by aeration at room temperature until it was used. Based on the dry matter, the starting concentration was adjusted to 2.5 ± 0.5 g/L DW (nominal value). - Duration of test (contact time):
- 25 d
- Parameter followed for biodegradation estimation:
- DOC removal
- % Degr.:
- 97.8
- Parameter:
- DOC removal
- Sampling time:
- 23 d
- Transformation products:
- no
- Volatile metabolites:
- no
- Validity criteria fulfilled:
- yes
- Conclusions:
- The primary degradation was calculated based on the total influent load, the total effluent load and the test item load adsorbed onto the activated sludge.
Primary biodegradation started as well directly after starting the application of Antimussol ZJ. The mean primary degradation during the plateau phase was 97.8 % - Executive summary:
The elimination and primary biodegradation of the test item Antimussol ZJ in an activated sludge unit was determined over a test period of 25 days according to OECD guideline 303 A. The study was conducted from 2015-08-31 to 2015-09-25 at the Dr.U.Noack-Laboratorien, 31157 Sarstedt, Germany.
The primary biodegradation was monitored by the decline of Antimussol ZJ in the effluent and activated sludge.
During acclimatization the activated sludge units had stabilized and biodegradation of the DOC of the organic medium became efficient (> 80 % after 2 days).
Due to variations in the quality and composition of the organic medium, the biodegradation decreased below 80 % periodically for 7 days. The decrease had no influence on the biodegradation efficiency, the unit worked efficiently throughout the test.
The nominal concentration of the test item stock solution was 500 mg/L. The stock solution was dosed at a constant rate of 0.25 pL/h into the activated sludge unit, resulting in a nominal influent concentration of 200 pg/L.
The elimination was calculated based on the influent and effluent concentrations. The primary degradation was calculated based on the total influent load, the total effluent load and the test item load adsorbed onto the activated sludge.
The amounts of Antimussol ZJ eliminated from the aqueous phase are summarized in Table 3. The mean elimination was 98.6 % (calculated day 19 to day 23 after test item application).
Primary biodegradation started as well directly after starting the application of Antimussol ZJ. The mean primary degradation during the plateau phase was 97.8 % .
Important note: Due to the preliminary character of this study, missing values had to be estimated (Effluent load, surplus sludge load). Therefore, when evaluating the biodegradation value of this study, these assumptions have to be kept in mind.
Referenceopen allclose all
Biodegradation of Organic Medium (DOC)
During acclimatization the activated sludge units had stabilized and biodegradation of the DOC of the organic medium became efficient (> 80 % after 2 days).
Due to variations in the quality and composition of the organic medium, the biodegradation decreased below 80 % periodically for 7 days. The decrease had no influence on the biodegradation efficiency, the unit worked efficiently throughout the test.
Elimination of Antimussol ZJ based on Specific LC-MS/MS Analysis
After the activated sludge units had stabilized, the dosage of the test item was started (September 2, 2015). Influent (stock solution) and effluent samples were analysed by LC- MS/MS.
The elimination of the test item was calculated based on influent and effluent concentrations. The plateau was considered to have been reached on day 19 after application of the test item.
The mean elimination was 98.6 % (calculated day 19 to day 23 after test item application).
Biodegradation of Antimussol ZJ based on Specific LC-MS/MS Analysis
The primary degradation was calculated based on the total influent load, the total effluent load and the test item load adsorbed onto the activated sludge.
Primary biodegradation started as well directly after starting the application of Antimussol ZJ. The mean primary degradation during the plateau phase was 97.8 % (Table 4).
Important note:Due to the preliminary character of this study, missing values had to be estimated. This was done for the effluent load by using the last measured value for dateswithout measurements. For the total surplus sludge load, the mean value of the measurements was used. Therefore, when evaluating the biodegradation value of this study, these assumptions have to be kept in mind.
Description of key information
OECD 303 A
The primary degradation was calculated based on the total influent load, the total effluent load and the test item load adsorbed onto the activated sludge.
Primary biodegradation started as well directly after starting the application of Antimussol ZJ. The mean primary degradation during the plateau phase was 97.8 %
Simulation testing on ultimate degradation in surface water
The study is scientifically not necessary because the substance is readily biodegradable
Sediment simulation testing
The study is scientifically not necessary because the substance is readily biodegradable
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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