Registration Dossier
Registration Dossier
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EC number: 227-497-9 | CAS number: 5858-81-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Not reported
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The information on acute oral toxicity has been evaluated. The original study reports with details on experimental set-up could not be retrieved.
- GLP compliance:
- not specified
- Remarks:
- no details included in the evaluation
- Test type:
- other: not specified
Test material
- Reference substance name:
- Disodium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate
- EC Number:
- 227-497-9
- EC Name:
- Disodium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate
- Cas Number:
- 5858-81-1
- Molecular formula:
- C18H12N2Na2O6S
- IUPAC Name:
- disodium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate
- Details on test material:
- Test substance: D&C Red 6; CI 15850
Batch: B2095 (LCW)
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 10 800 mg/kg bw
- Based on:
- test mat.
- Clinical signs:
- other:
Applicant's summary and conclusion
- Conclusions:
- Based on the evaluated high LD50 value of ≥ 5000 mg/kg bw, Pigment Red 57 is reported to to be of low acute oral toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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