Registration Dossier
Registration Dossier
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EC number: 245-396-8 | CAS number: 23047-25-8
Endpoint summary
Administrative data
Description of key information
A skin corrosion/irritation prediction was obtained from a Toxtree model.
Moreover an eye irritation prediction was obtained from a Toxtree model.
In both cases, the corrosivity can be excluded.
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Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation / corrosion, other
- Type of information:
- other: Extimation by a decision tree
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Results are derived from a valid Toxtree application, but with limited documentation/justification
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- The substance is extimated as not corrosive to skin. Anyway the applied decision tree is not able to extimate irritating properties. Results can not be uses for classification purposes.
Reference
The substance is extimated as not corrosive to skin.
The following input data were reported:
- Melting point= 105 °C
- Lipid solubility= silent, since no data ias available
- Water solubility= 0.00204 g/L
Eye irritation
Link to relevant study records
- Endpoint:
- eye irritation, other
- Type of information:
- other: Extimation by a decision tree
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Results are derived from a valid Toxtree application, but with limited documentation/justification
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- The substance is extimated as not irritating to eye.
Reference
The substance is extimated as not irritating to eye (R41).
The following input data were reported:
- Melting point= 105 °C
- Lipid solubility= silent, since no data is available
- Water solubility= 0.00204 g/L
Additional information
Justification for classification or non-classification
A skin corrosion/irritation prediction was obtained from a Toxtree model.
The substance is considered not to be corrosive for skin, however the model is not able to exclude the skin irritation.
The study cannot be used for classification.
Besides an eye irritation prediction was obtained from a Toxtree model.
The substance is estimated as not irritant to eye (R41 – H318).
The study cannot be used to exclude the classification as H319.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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