Diammonium 5-(hexylsulfonyl)-2-{[3-methyl-2,7-dioxo-1-(3-sulfonatobenzoyl)-2,7-dihydro-3H-naphtho[1,2,3-de]heterocycle-6-yl]amino}benzenesulfonate

Density

Administrative data

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

08 January 2009 to 26 February 2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Date of inspection: 19 August 2008; Date of signature: 04 March 2009

Type of method:

pycnometer method

Test material

Test material information

Results and discussion

Density

Type:

relative density

Density:

1.41

Temp.:

21 °C

Any other information on results incl. tables

Calibration

The pressure readings (P₁and P₂) and the calculated volume for the calibration ball are shown in the following table:

Table 2

Determination	P1	P2	Volume (cm^3)	Certified Volume (cm^3)	Tolerance (cm^3)
A	17.159	8.490	56.354	56.6	± 0.5
B	17.021	8.423	56.382	56.6	± 0.5

Sample

The pressure readings, calculated volumes and density values obtained for the test material are shown in the following table:

Table 3

Determination	P1	P2	Volume (cm^3)	Density (kg/m^3)
A	17.002	7.348	29.729	1.40 x 10^3
B	17.042	7.487	33.150	1.42 x 10^3

Temperature: 21.0 ± 0.5ºC
Mean density:           1.41 x 10³ kg/m³
Relative density:       1.41

Applicant's summary and conclusion

Conclusions:

The relative density of the test material has been determined to be 1.41 at 21.0 ± 0.5°C.

Executive summary:

1.41 at 21.0 ± 0.5°C, using a gas comparison pycnometer, Method A3 Relative Density of Commission Regulation (EC) No 440/2008 of 30 May 2008.