Registration Dossier
Registration Dossier
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EC number: 807-710-7 | CAS number: 532410-39-2
Endpoint summary
Administrative data
Description of key information
ACD/Percepta model for acute oral toxicity on mouse and rat provides LD50predictions for mice by oral administration route,based on the GALAS methodology. Reliability of predictions is estimated in terms of reliability index (RI),which ranges from0 to 1 and takes into account the similarity of the target with the training set compounds and the consistency of experimental values for similar compounds.
For tert-Butyl methyl(2-oxopropyl)carbamate, ACD/Percepta provided :
- in mouse an LD50 prediction equal to 1800 mg/kg, and the prediction was assessed as moderate reliable being the reliability index equal to 0.67;
in rat an LD50 prediction equal to 2800 mg/kg, and the prediction is assessed as moderate reliable being the reliability index equal to 0.70.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
Additional information
Justification for classification or non-classification
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