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Diss Factsheets
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EC number: 238-620-0 | CAS number: 14576-08-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Abiotic degradation:
Air: Based on estimation with the QSAR model Aopwin the substance undergoes in air rapid degradation after reaction with hydroxyl radicals or ozone. The DT50 values after reaction with hydroxyl radicals and ozone are 1.3 hours and 0.64 hours respectively. The substance will not reach the stratosphere and is therefore not considered to be a long-range transported chemical in air. The substance does not have an ozone depletion potential because it does not contain halogens and does not have the potential to reach the stratosphere (GHS, 3rd Edition, CLP, 2008).
Water: No experimental information is available on the hydrolysis of this substance. Performance of a test is waived as the substance is readily biodegradable. Hydrolysis is however not expected based on structural grounds and the hydrolysis half-life determined at 1 year at 25 °C.
Biotic degradation:
The biodegradation potential of the substance in water was determined in a screening study according to OECD TG 301F. Under the conditions of the test the substance was readily biodegradable.
Bioaccumulation:
Bioaccumulation in aquatic species is based on the available information (measured log Kow of 4.5 and calculated BCF values) and is deemed sufficient for the chemical safety assessment. The BCFs for aquatic and terrestrial organisms were calculated using QSARs of Veith et al. (1979) and Jager (1998), both incorporated in the EUSES model, and yielded values of 1330 and 380 L/kg ww, respectively.
Transport and distribution:
A measured Koc value of 700 L/kg w.w. (log Koc 2.85) indicates that the substance has low potential to adsorb to sediment/soil (ECHA guidance 7b section 7.8.7)
To assess the volatilisation potential of the substance a Henry's law constant was calculated which showed a value of 21.9 and 10.5 Pa. m3/mol at 25oC and 12°C, respectivelty. Based on this value partitioning from water to air may be expected.
Based on Level III environmental distribution modelling using EPISUITE (assuming equal and continuous releases to air, water and soil) using the CAS number 14576 -08 -0, it is estimated that the majority of the substance released to the environment will partition mainly into soil (84.4%) and water (15.2%) with minor amounts to sediment and air (both <1%).
The SimpleTreat model, which is incorporated in EUSES, simulates the distribution of the substance in a Sewage Treatment Plant. Model calculations show that 80% of the substance will be degraded and that 6.0%, 11.1% and 2.95% will partition to sewage sludge, water and air, respectively, using measured physico-chemical properties including Koc.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.