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Diss Factsheets
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EC number: 943-438-6 | CAS number: 90063-59-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no data available: testing technically not feasible
Marine water
- Hazard assessment conclusion:
- no data available: testing technically not feasible
STP
- Hazard assessment conclusion:
- no data available: testing technically not feasible
Sediment (freshwater)
- Hazard assessment conclusion:
- no data available: testing technically not feasible
Sediment (marine water)
- Hazard assessment conclusion:
- no data available: testing technically not feasible
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no data available: testing technically not feasible
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no data available: testing technically not feasible
Additional information
Conclusion on classification
For Litsea cubeba oil, acute toxicity studies for three trophic levels are available. The EL50 and LL50 for daphnia and fish respectively, were both 4.2 mg/L. While for algae, an ErL50 and NOErL of 25 and 10 mg/L were derived. Based on the lowest available acute data of 4.2 mg/L from the daphnia and fish studies, the substance does not need to be classified for acute aquatic toxicity according to Table 4.1.0 (a) of CLP.
As only one chronic value is available (Algae 72h-NOErL of 10 mg/L), the aquatic chronic classification needs to be derived on both chronic and acute toxicity data and the most stringent outcome needs to be taken into consideration. Based on the NOErL, Litsea cubeba oil does not require classification for chronic toxicity. However, in view of the substance being readily biodegradable, a log Kow range of 2.06 - 6.3. (16.90% of the constituents has a log Kow >= 4) and the lowest acute data point being 4.2 mg/L for fish and daphnia, the substance needs to be classified for long term aquatic toxicity according to Figure 4.1.1 and Table 4.1.0, (b) iii of CLP, resulting in aquatic Chronic Category 2 (H411) classification.
As the worst case needs to be taken, Litsea cubeba oil needs to be classified Chronic Category 2 (H411) according to EU CLP (EC 1272/2008 and its updates). M factor for acute and chronic toxicity is not applicable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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