Litsea cubeba, ext.

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

22/08/2012

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Non-GLP study according to methodology comparable to international guideline (OECD guideline 103).

Reason / purpose for cross-reference:

reference to same study

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

no

Principles of method if other than guideline:

200 ml (178.0 g) of sample were heated by means of a hemispherical heating mantle. Bottom and head temperatures and amount of distillate were read and correlated to the distillation time to develop a distillation curve diagram. Samples were stored in full bottles at room temperature prior to testing.

GLP compliance:

no

Type of method:

distillation method

Boiling pt.:

83 °C

Atm. press.:

1 013 hPa

Remarks on result:

other: Standard deviation: +/- 10ºC

Time (h)	Bottom Temperature (°C)	Head Temperature (°C)	Amount of Distillate (g)	Amount of Distillate (%)	Comments
00:00	25	24
00:04	44	24
00:09	73	24
00:14	110	25
00:15	117	25
00:16	125	25
00:17	133	25
00:18	141	25
00:19	149	25			start of boiling
00:20	157	25
00:21	166	25
00:22	175	25
00:23	182	25
00:24	188	25
00:25	198	26
00:26	206	70
00:27	212	83	0.21	0.12	first distillate
00.28	216	90	0.43	0.24
00:29	221	128	0.78	0.44
00:30	226	167	4.11	2.31
00:31	231	185	14.44	8.11
00.32	235	213	32.09	18.03
00.33	236	216	54.0	30.34
00.34	237	218	80.02	44.95	End distillation

Observations:

·        The sample started to boil at a bottom temperature of 149°C

·        First distillate was obtained at 83°C (head temperature)

·        Head temperature reached a plateau around 218°C

·        Bottom temperature continued to rise due to composition change.

Conclusions:

The boiling point of Litsea cubeba essential oil is 83ºC at 1013 hPa.

Executive summary:

The boiling point of Litsea cubeba essential oil was determined according to methodology comparable to OECD guideline 103 using the distillation method. The boiling point (first distillate) was found to be 83 +/- 10ºC at 1013 hPa.

Description of key information

The boiling point of Litsea cubeba essential oil was determined according to methodology comparable to OECD guideline 103 using the distillation method. The boiling point (first distillate) was found to be 83 +/- 10ºC at 1013 hPa.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

83 °C