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EC number: 278-585-9 | CAS number: 76994-37-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In an acute immobilization test with Daphnia magna Straus a 48-h EC50 of 0.028 mg/L (based on nominal concentrations) was determined for the test item (BASF 50E0469/14X513, 2016).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.028 mg/L
Additional information
Key study (BASF 50E0469/14X513, 2016):
Immobilization of Daphnia magna exposed to the test item was
investigated during a 48-hour semi-static test with daily renewals
according to OECD guideline 202 (2004). The water fleas were exposed to
a control and the following nominal test item concentrations: 0.0039,
0.0086, 0.019, 0.041, 0.091, 0.20, 0.45, 1.0 and 2.2 mg/L. The Daphnia
magna were observed for immobilization after 24 and 48 hours of
exposure. The test item was not stable under the test conditions within
24 hours. Therfore, the endpoint values were calculated based on nominal
concentrations.
In the control and in the test item concentration of 0.0039 mg/L no immobilization was observed during exposure. At exposure termination in the test item concentrations of 0.0086, 0.019, 0.041 and 0.091 mg/L immobilization was 10, 45, 60 and 85 %, respectively. In the test item concentrations 0.20, 0.45, 1.0 and 2.2 mg/L the immobilization was 100 %. The endpoint values were based on the nominal test item concentrations after 48 h and are given below:
The EC50/ 48 h value is 0.028 mg/L (95%
confidence interval 0.021 – 0.038)
The LOEC/ 48 h value is 0.019 mg/L
The NOEC/ 48 h value is 0.0086 mg/L
Supporting read across study (BASF 1/90/0937/50/1, 1990):
The acute immobilization test with Daphnia magna (STRAUS) was assessed in an immobilization test. In this test young Daphnia magna STRAUS (< 24 h old) were exposed to the read across test substance (CAS 83968-15-4) for 48 hours according to Directive 79/831/EEC Annex V, Part C (1989) under non-GLP conditions. The nominal concentrations were 0.0009, 0.0019, 0.0039, 0.0078, 0.0156, 0.0312, 0.0625, 0.125, 0.250, 0.5, 1 mg/L and a control (0 mg test item/L). No concentrations were measured. The study encompassed 4 replicates per concentration and 4 replicate per control. The number of the organisms per vessel was 5. The mobility of the Daphnia was determined by visual observation after 3, 6, 24 and 48 hours. No reference substance as positive control was tested. The 48h-EC0 was determined to be 0.0625 mg/L and the 48h-EC50 was determined to be 0.12 mg/L. All reported results refer to the nominal concentrations.
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