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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1982
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
1982

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
not specified
Test type:
other: LC50

Test material

Constituent 1
Chemical structure
Reference substance name:
Trichlorosilane
EC Number:
233-042-5
EC Name:
Trichlorosilane
Cas Number:
10025-78-2
Molecular formula:
Cl3HSi
IUPAC Name:
trichlorosilane

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: no data
Type of inhalation exposure:
not specified
Vehicle:
other: no data
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
2 h
Concentrations:
No data
No. of animals per sex per dose:
No data
Control animals:
not specified

Results and discussion

Effect levels
Dose descriptor:
LC50
Effect level:
1.5 mg/L air
Based on:
test mat.
Exp. duration:
2 h

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
In an acute inhalation toxicity study, not conducted according to OECD Test Guideline and not specified if in compliance with GLP, a 2-hour LC50 value of 1.5 mg/l in the mouse was reported in IUCLID 2000. No further details are available.