Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 220-912-4 | CAS number: 2935-90-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Methyl 3-mercaptoproprionate was considered a non-sensitiser in a mouse local lymph node assay (Harlan Laboratories, Ltd, 2010). Stimulation indices (SI) were 2.87, 2.14 and 2.44 for 5, 10 and 25% methyl 3-mercaptoproprionate (in 4:1 acetone/olive oil), respectively.
Migrated from Short description of key information:
Methyl 3-mercaptoproprionate was considered a non-sensitiser in a mouse local lymph node assay.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
No data have been found concerning respiratory sensitisation and there are no indications that methyl 3-mercaptoproprionate is a respiratory allegen.
Migrated from Short description of key information:
There are no specific data on respiratory sensitisation.
Justification for classification or non-classification
There is sufficient evidence to indicate that methyl 3-mercaptoproprionate is not a skin sensitiser and no classification is warranted for this endpoint under EU Dir. 67/548/EEC or GHS/CLP.
Although there are no data on respiratory sensitisation, there is no evidence that classification is warranted for this endpoint under EU Dir. 67/548/EEC or GHS/CLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
