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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation
Remarks:
no data
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2000
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Basic information from IUCLID4 dataset only.
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
other: IUCLID4
Title:
Unnamed
Year:
2000
Report date:
2000

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: U.S. DHEW / Fed. Reg. 37, 8534, 1972
Deviations:
not applicable
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
O,O-diethyl phosphorochloridothioate
EC Number:
219-755-4
EC Name:
O,O-diethyl phosphorochloridothioate
Cas Number:
2524-04-1
Molecular formula:
C4H10ClO2PS
IUPAC Name:
O,O-diethyl chlorophosphonothioate
Details on test material:
- Name of test material (as cited in study report): O, O-diethyl phosphorochloridothioate

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Test system

Vehicle:
not specified
Controls:
not specified
Duration of treatment / exposure:
not applicable
Observation period (in vivo):
not applicable
Number of animals or in vitro replicates:
not applicable

Results and discussion

In vivo

Irritant / corrosive response data:
No detailed information on the method are provided. It is stated that the test substance is corrosive.
Other effects:
not applicable

Any other information on results incl. tables

No other information.

Applicant's summary and conclusion

Interpretation of results:
corrosive
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
The test substance is stated to be corrosive.
Executive summary:

In the IUCLID4 dataset on O,O-diethyl phosphorochloridothioate the result of an eye irritation test in rabbits is presented and it is stated that the test substance is corrosive.