Registration Dossier
Registration Dossier
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EC number: 215-542-5 | CAS number: 1330-61-6
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
After 5 days at pH 4 and 7, the test item was shown to have hydrolysed by less than 10% compared to T0. This indicated that it was hydrolytically stable and significant hydrolysis had not occurred under these conditions.
After 5 days at pH 1.2 and 9, the test item was shown to have hydrolysed by more than 10% compared to T0. This indicated that it was hydrolytically unstable and significant hydrolysis had occurred under these conditions.
The half life of the test item at pH 1.2 was determined to be 2.4 days.
The half life of the test item at pH 9.0 was determined to be 10.3 days.
Hydrolysis was shown to have formed isodecanol and postulated to have formed acrylic acid.
Key value for chemical safety assessment
Additional information
The hydrolysis of the test item was assessed in aqueous buffers at pH 1.2 4, 7 and 9 at 50 ± 0.5 °C.
After 5 days at pH 4 and 7, the test item was shown to have hydrolysed by less than 10% compared to T0. This indicated that it was hydrolytically stable and significant hydrolysis had not occurred under these conditions.
After 5 days at pH 1.2 and 9, the test item was shown to have hydrolysed by more than 10% compared to T0. This indicated that it was hydrolytically unstable and significant hydrolysis had occurred under these conditions.
The half life of the test item at pH 1.2 was determined to be 2.4 days.
The half life of the test item at pH 9.0 was determined to be 10.3 days.
Hydrolysis was shown to have formed isodecanol and postulated to have formed acrylic acid.
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