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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2003
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: ECB/TM/February 1996
Version / remarks:
EUROPEAN COMMISSION, Directorate General XII-JRC, Science Research and Development-Joint Research Centre. Particle Size Distribution, Fibre Length and Diameter Distribution Guidance Document, ECB/TM/February 1996.
Deviations:
no
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Percentile:
D50
Mean:
< 16.8 µm
Remarks on result:
other: SD= 0.053(migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.)
Percentile:
D10
Mean:
< 4.9 µm
St. dev.:
0.191
Percentile:
D90
Mean:
< 25.9 µm
St. dev.:
1.379

The test was performed with two samples of the stock dispersion and each measured in duplicate by the laser scattering / diffraction.

Conclusions:
The particle size distribution of test substance was determined to be MMD= 16.8 µm
Executive summary:

In this guideline (ECB/TM February 1996) study conducted to GLP standards, the test material (EC 444-860-9) was determined to have a particle size distribution of MMD= 16.8 µm.

Description of key information

Study conducted to recognised testing guidelines with GLP.

Additional information

The measurement was performed with two samples of the stock dispersion and each measured in duplicate by the laser scattering / diffraction.

MMD= 16.8 µm
D10= 4.9 µm
D90= 25.9 µm