Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The data comes from a report of NATIONAL INDUSTRIAL CHEMICALS NOTIFICATION AND ASSESSMENT SCHEME (NICNAS), which is administered by the National Occupational Health and Safety Commission (NOHSC) of Australian Commission. Also the physico-chemical properties were determined using OECD test methods.

Data source

Reference
Reference Type:
review article or handbook
Title:
Phosphoric acid, (1-methylethylidene) di-4,1-phenylene tetraphenyl ester (Fyrolflex BDP)
Author:
National Occupational Health and Safety Commission (Australia)
Year:
2000
Bibliographic source:
NATIONAL INDUSTRIAL CHEMICALS NOTIFICATION AND ASSESSMENT SCHEME

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Principles of method if other than guideline:
n.a.
GLP compliance:
not specified
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
>= 6
Temp.:
25 °C
pH:
> 5.5 - < 6
Details on results:
The retention time of the test compound on C18 columns was compared with those for five reference compounds of known Pow. The reference compounds included thiourea, bromobenzene, diphenyl, dibenzyl and 2,4-DDT.

Any other information on results incl. tables

The retention times of the substance on the column were such that all components have log Pow > 6, indicating high affinity for the oil phase. Large values of log Pow could be expected for the substance as it contains a high proportion of aromatic or aliphatic hydrocarbon.

Applicant's summary and conclusion