Registration Dossier

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1997

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 402 (Acute Dermal Toxicity)
GLP compliance:
yes (incl. certificate)
Test type:
standard acute method
Limit test:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Remarks on result:
other: limited test
Mortality:
no death
Clinical signs:
No signs of systemic toxicty were observed during the observation period.


Body weight:
All animals showed expected gain in bodyweight
Gross pathology:
No signs of skin irritation were noted during the study. No abnormalities were noted at necropsy.

Other findings:
Nothing to add in this field.

Any other information on results incl. tables

Mortality: No deaths were recorded.

Clinical observations: No clinical signs of toxicity were noted.

Morphological findings: No signs of skin irritation were noted during the study. No abnormalities were noted at necropsy.

Comment: All animals showed expected gain in bodyweight.

LD50: > 2 000 mg/kg

Result: The test chemical was of low dermal toxicity in rats.

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: expert judgment
Conclusions:
The test material has low toxicity via acute dermal toxicity study in rats.
Executive summary:

According to OECD TG 402, the acute dermal toxicity test was well conducted and the results indicated the test material has very low toxicity in rats.