Registration Dossier
Registration Dossier
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EC number: 700-728-5 | CAS number: 74805-60-0
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2020-11-30 to 2020-12-04
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 2014
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
Test material
- Reference substance name:
- (5Z)-5-(phenylmethylidene)imidazolidine-2,4-dione
- EC Number:
- 700-728-5
- Cas Number:
- 74805-60-0
- Molecular formula:
- C10H8N2O2
- IUPAC Name:
- (5Z)-5-(phenylmethylidene)imidazolidine-2,4-dione
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Water solubilityopen allclose all
- Key result
- Water solubility:
- 82.4 mg/L
- Conc. based on:
- test mat.
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- 6.8
- Water solubility:
- 91.6 mg/L
- Conc. based on:
- test mat.
- Incubation duration:
- 48 h
- Temp.:
- 20 °C
- pH:
- 6.8
- Water solubility:
- 95.1 mg/L
- Conc. based on:
- test mat.
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- 6.9
Any other information on results incl. tables
Water Solubility Results at 20°C for n-Butyltriphenylphosphonium bromide
Preincubation time |
Replicat No. |
Concentration [mg/L] |
Mean [mg/L] |
Measured pH |
Tyndall-Effect |
24 h |
1 |
83.1 |
82.4 |
6.994 |
negative |
2 |
81.8 |
6.775 |
negative |
||
48 h |
1 |
98.5 |
91.6 |
6.987 |
negative |
2 |
84.6 |
6.600 |
negative |
||
72 h |
1 |
104.8 |
95.1 |
6.807 |
negative |
2 |
85.3 |
6.920 |
negative |
||
Mean (48 -72 h) |
|
|
93.3 |
6.868 |
negative |
Deviation [%] (24-72 h) |
|
|
3.8 |
|
|
Applicant's summary and conclusion
- Conclusions:
- The water solubility of the test item is 93.3 mg/L (20°C, pH 6.9). The water solubility was determined according to OECD guideline 105 (1995) and Council Regulation (EC) No. 260/2014, Method A.6 using the flask method at 20 ± 0.5°C with pre-incubation at 30 ± 0.5°C.
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