Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
column elution method
Key result
Water solubility:
0.67 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
>= 10 - <= 11
Conclusions:
The BENZYL ISO EUGENOL solubility in water at 20 ± 0.5 °C based on the mean of the two determinations with the column elution method was 0.670 mg/L.
Executive summary:

A study was performed to assess the water solubility of the test item BENZYL ISO EUGENOL by the column elution method.

This method is based on the elution of the test item with water from a micro-column charged with an inert support material (celite), previously coated with an excess of the test item. The water solubility was given by the mass concentration of the eluate when this has reached a plateau as a function of time. A second experiment was performed at half the flow rate. The test item concentration was regularly measured by HPLC-DAD.

The BENZYL ISO EUGENOL solubility in water at 20 ± 0.5 °C based on the mean of the two determinations with the column elution method was             0.670 mg/L.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion