Registration Dossier
Registration Dossier
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EC number: 212-611-1 | CAS number: 831-82-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: no specified
- Expiration date of the lot/batch: no specified
- Purity test date: pure (99%)
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
not specified
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
not specified - Analytical monitoring:
- yes
- Details on sampling:
- No specified
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: not specified
- Controls: Concurrent control - Test organisms (species):
- Pimephales promelas
- Details on test organisms:
- TEST ORGANISM
- Common name: Pimephales (bluntnose minnows)
- Strain: Cypriniformes (minnows, suckers)
- Source: Laboratory
- Age at study initiation (mean and range, SD): 30 days
- Length at study initiation (length definition, mean, range and SD): not specified
- Weight at study initiation (mean and range, SD): not specified
- Method of breeding: not specified
- Maintenance of the brood fish: not specified
ACCLIMATION
not specified
FEEDING DURING TEST
not specified - Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- 44.8 milligrams per liter Calcium carbonate
- Test temperature:
- 24.9
- pH:
- 7.54
- Dissolved oxygen:
- 6.2 mg/L
- Salinity:
- 50 milligrams per liter Calcium carbonate
- Conductivity:
- Not specified
- Nominal and measured concentrations:
- 6 doses
- Details on test conditions:
- Not specified
- Reference substance (positive control):
- not specified
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 4.75 - < 6 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 4.75 - < 6 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 4.75 - < 6 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 4.55 - < 5.38 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 4.75 - < 6 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- behaviour
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 4.75 - < 6 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- behaviour
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 4.75 - < 6 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- behaviour
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 4.55 - < 5.38 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- behaviour
- Details on results:
- Not specified
- Results with reference substance (positive control):
- Not specified
- Validity criteria fulfilled:
- yes
- Conclusions:
- The LC50, 48h for 4-phenoxyphenol is ]4.75 - 6] mg/L.
- Executive summary:
The LC50, 48h for 4-phenoxyphenol is ]4.75 - 6[ mg/L.
Reference
Description of key information
The LC50, 48h for 4-phenoxyphenol is ]4.75 - 6[ mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 4.8 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
