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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
3 hour EC50 > 1000 mg/L, activated sludge, OECD 209, EU Method C.11, Oláh (2014)
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
Additional information
In the key study (Oláh 2014), the toxicity of a structural analogue of the registered material to microorganisms was determined in an activated sludge respiration inhibition test conducted in accordance with the standardised guidelines OECD 209 and EU Method C.11. The study was performed under GLP conditions. The study was therefore assigned a reliability score of 2 in accordance with the principles for assessing data quality as defined in Klimisch et al. (1997).
Activated sewage sludge (obtained from a domestic sewage treatment plant) was incubated for 3 hours under aeration with the test material at concentrations of 10, 100 and 1000 mg/L. At the end of the incubation period, the oxygen respiration rate was measured over a period of 15 minutes with an oxygen electrode. Blank, abiotic and positive controls were run in parallel for comparison of respiration rates and also to confirm the validity of the test.
The average of specific respiration rate of the blank controls was 14.05 mg O₂/L/h/g solid. The coefficient of variation of oxygen uptake rate in untreated replicates was 7.53 %. The oxygen uptake rate of the blank controls should be >20 mg O₂/L/h/g; however, the high EC50 obtained for the test material and the good results obtained with the positive control indicate that this did not affect the validity of the test.
The average total respiration rate of the treated parallel mixtures for the test material concentrations at 10, 100 and 1000 mg/L were 14.04, 12.10 and 8.44 mg/L/hour, respectively.
The average respiration rate of the abiotic parallels was 0.46 mg O₂/L/h.
The average inhibition values for 10, 100 and 1000 mg/L were 1.85, 20.58 and 37.23 %, respectively.
Under the conditions of the test, the EC50 of the test material to activated sludge was determined to be greater than 1000 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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