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EC number: 939-579-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
OECD 201, EU Method C.3, GLP, key study, validity 2:
72h-EC50 = 2.43 mg dry extract/L based on biomass;
72h-NOEC = 0.54 mg dry extract/L based on biomass.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 2.43 mg/L
- EC10 or NOEC for freshwater algae:
- 0.54 mg/L
Additional information
One key study is available to assess the toxicity of Chimexane HB to algae (Scenedesmus subspicatusnow calledDesmodesmus subspicatus). This study was performed according to OECD 201 and Commission EC Method C.3 with GLP statement, under static condition during 72 hours.
Five nominal test item concentrations were used (1.0, 2.2, 4.6, 10.0 and 21.6 mg/L) with 3 replicates per concentration. A control group (6 replicates not exposed to any substance) was also employed under the same experimental conditions. Test media were continuously mechanically stirred, and randomly rotated each study day. Algal cell concentrations have been measured approximately 24, 48 and 72 hours after the start of the study. Measurements of pH were performed for each test and control medium, at the start and at the end of the study. No analytical monitoring of the test item concentrations was performed. Concentrations levels of the test substance throughout the study period were guaranteed by the use of axenic algal strain and by the known water-solubility and physico-chemical stability of the test substance in the experimental conditions.
The endpoint values were recalculated with ToxRat Professional. Results are expressed in term of test material (aqueous content of 45.9%), each value has to be multiplied by 0.541 to be comparable to the other ecotoxicological data.
The results are presented below:Growth rate:
72h-ErC50 = 11.09 mg test item/L, corresponding to 6.0 mg dry extract/L;
72h-ErC10 = 3.19 mg test item/L, corresponding to 1.73 mg dry extract/L;
72h-NOECr = 2.2 mg test item/L, corresponding to 1.19 mg dry extract/L.
Biomass:
72h-EbC50 = 4.49 mg test item/L, corresponding to 2.43 mg dry extract/L;
72h-EbC10 = 1.91 mg test item/L, corresponding to 1.03 mg dry extract/L;
72h-NOECr = 1.0 mg test item/L, corresponding to 0.54 mg dry extract/L.
In conclusion, considering that one criterion for control’s specific growth rate was not fulfilled, lowest data have to be retained:
72h-EbC50 = 2.43 mg dry extract/L; 72h-NOECb = 0.54 mg dry extract/L.
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