Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19.7.1991-30.7.1991
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods

Data source

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: National acute toxicity testing of Soviet Union (internal)
Version / remarks:
According to 1990 standard, method and measurement approved by Ministery of Health
GLP compliance:
not specified

Test animals

Species:
mouse
Strain:
other: CBWA
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
unchanged (no vehicle)
No. of animals per sex per dose:
30
Control animals:
yes

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 800 mg/kg bw
Based on:
test mat. (total fraction)

Any other information on results incl. tables

As a reference, 2 shampoos/surfactants were used, with 30 mice in each reference test.

Applicant's summary and conclusion

Conclusions:
The measured acute toxicity is 800 mg/kg
Executive summary:

The measured acute toxicity is 800 mg/kg