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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- 17 Jul 1992
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Kurume central sewage treatment center (Kurume-shi, Fukuoka, Japan); obtained on 04 Oct 2017
- Method of cultivation: After collection, the activated sludge was aerated at the test temperature until it was used für the test. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to guideline
- Test temperature: 22 °C
- pH: 7.3
- Suspended solids concentration: 30 mg/L
- Continuous darkness: yes
- Other: Each test solution was stirred with a stirrer.
TEST SYSTEM
- Culturing apparatus: Closed system oxygen consumption measuring apparatus (glass vessels)
- Number of culture flasks/concentration: 2
- Measuring equipment: automated measuring system
- Test performed in closed vessels due to significant volatility of test substance: yes
- Test performed in open system: no
- Details of trap for CO2 and volatile organics if used: Soda lime was used for absorption of evolved CO2.
SAMPLING
- Sampling frequency: O2 consumption was measured continuously.
- Sampling method: Automated measuring method.
- Other: During the incubation period, the appearance of the test solutions was observed once a day.
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes, two vessels
- Toxicity control: yes, one vessel
- Reference substance: yes, one vessel - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 4
- Sampling time:
- 28 d
- Details on results:
- The toxicity control resulted in a degradation of 35% after 14 d.
Undissolved material was oberserved in the test vessels during exposure. - Results with reference substance:
- The reference substance was degraded to 89% after 14 d.
- Validity criteria fulfilled:
- yes
- Remarks:
- For further details please refer to “Any other information on results incl. tables”.
- Interpretation of results:
- under test conditions no biodegradation observed
Reference
Table 1: % degradation of the test item, reference item and toxicity control
|
7 d |
14 d |
21 d |
28 d |
Average |
||||
BOD [mg] |
% degradation |
BOD [mg] |
% degradation |
BOD [mg] |
% degradation |
BOD [mg] |
% degradation |
% degradation |
|
Test item |
4.8 |
2 |
6.9 |
3 |
8.2 |
3 |
9.4 |
4 |
4 |
Test item |
4.7 |
2 |
6.5 |
2 |
7.5 |
3 |
8.3 |
3 |
|
Toxicity control |
45.7 |
33 |
50.3 |
35 |
53.3 |
37 |
55.2 |
38 |
- |
Blank |
3.5 |
- |
4.9 |
- |
5.7 |
- |
6.4 |
- |
- |
Blank |
3.3 |
- |
4.6 |
- |
5.4 |
- |
6.0 |
- |
- |
Reference item |
44.6 |
82 |
49.5 |
89 |
52.3 |
93 |
54.0 |
95 |
- |
Table 2: Validity criteria for OECD 301.
Criterion from the guideline |
Outcome |
Validity criterion fulfilled |
Difference of extremes of replicate values of the removal of the test chemical at the plateau, at the end of the test or at the end of the 10-d window, as appropriate, is less than 20%. |
1% |
yes |
Percentage degradation of the reference compound has reached the pass levels by day 14. |
89% |
yes |
The oxygen uptake of the inoculum blank is normally 20-30 mg O2/L and should not be greater than 60 mg/L in 28 days. |
21 mg/L |
yes |
The toxicity control should degrade to at least 25% (based on ThOD or ThCO2) within 14 d. |
35% after 14 d |
yes |
Description of key information
Not readily biodegradable: 4% (O2 consumption, OECD 301F)
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
One experimental study is available investigating the biodegradability of Fatty acids C16-18 (even numbered), oligoesters with sucrose. The study was performed according to OECD 301 F (GLP) with activated sludge from a domestic sewage treatment plant as inoculum. 100 mg of the test item was incubated with the activated sludge and the O2 consumption was followed continuously. In addition to the culture flasks with the test item a toxicity control containing both, test item and reference substance, as well as a positive control were run in parallel. After 28 d, 4% degradation of the test item was recorded indicating that Fatty acids C16-18 (even numbered), oligoesters with sucrose is not readily biodegradable according to the OECD criteria. The toxicity control resulted in a degradation of 35% after 14 d. Since the trigger of 25% degradation after 14 d is passed the test item is not considered to be inhibitory to the inoculum.
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