Registration Dossier
Registration Dossier
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EC number: 224-658-5 | CAS number: 4439-24-1
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 012
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Data from handbook; no guideline or method described.
- GLP compliance:
- not specified
- Test type:
- other: Not specified
Test material
- Reference substance name:
- 2-(2-methylpropoxy)ethanol
- EC Number:
- 224-658-5
- EC Name:
- 2-(2-methylpropoxy)ethanol
- Cas Number:
- 4439-24-1
- Molecular formula:
- C6H14O2
- IUPAC Name:
- 2-(2-methylpropoxy)ethan-1-ol
Constituent 1
Test animals
- Species:
- rabbit
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- >= 200 - <= 400 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- Category 3 based on GHS criteria
- Conclusions:
- Based on an dermal LD50 range of 200-400 mg/kg bw for rabbit, the substance meets the criteria for classification as Acute toxicity Category 3 via dermal route in accordance with Regulation (EC) N° 1272/2008.
- Executive summary:
A dermal LD50 of 200 -400 mg/kg bw for rabbit was reported in a toxicology handbook. No inforamtion on the test method was given. Based on the reported values the substance meets the criteria for Acute toxicity Category 3 via the dermal route in accordance with Regulation (EC) N° 1272/2008.
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