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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: peer-reviewed database

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Cobalt carbonyl (10210-68-1)
Author:
International Chemical Safety Card (ICSC) database
Year:
2017
Bibliographic source:
International Program on Chemical Safety/European Commission; ICSC No. 0976 (Peer Review Status: April 11, 2014, Validated). Available from, as of January 10, 2017: http://www.inchem.org/documents/icsc/icsc/eics0976.htm
Reference Type:
secondary source
Title:
TOXNET
Author:
HSDB database
Year:
2004
Bibliographic source:
https://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
not specified in database
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Octacarbonyldicobalt
EC Number:
233-514-0
EC Name:
Octacarbonyldicobalt
Cas Number:
10210-68-1
Molecular formula:
C8O8Co2
IUPAC Name:
1,1,1,3,3,3-hexakis(oxidaniumylidynemethyl)-2,4-dioxo-1,3-dicobaltabicyclo[1.1.0]butane-1,1,3,3-tetrakis(ylium)

Results and discussion

In vitro

Results
Irritation parameter:
other: not specified
Remarks on result:
other: the substance is irritating to the eyes

Applicant's summary and conclusion

Conclusions:
substance is irritating to the eyes
Executive summary:

There is no available information on the methods used to determine the value for this endpoint. However, this information is taken from ICSC /HSDB database which is considered to be a reliable peer reviewed databases. The substance is reported to be irritating to the eyes.