2-bromo-5-hydroxy-4-methoxybenzaldehyde

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1998-03-04 to 1998-04-16

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1998

Report date:

1998

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Principles of method if other than guideline:

not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

Certificate from the Swiss GLP Monitoring Authority.

Type of method:

other: Differential Thermal Calorimeter & Capillary Tester

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

426-540-0

EC Name:

-

Cas Number:

2973-59-3

Molecular formula:

C8 H7 Br O3

IUPAC Name:

2-bromo-5-hydroxy-4-methoxybenzaldehyde

Test material form:

solid

Specific details on test material used for the study:

- Batch: 00265786
- Purity: 91.3% (HPLC purity)
- Expiration date: July 1, 1998 (retest date)
- Storage: at room temperature at about 20°C

Results and discussion

Boiling point

Boiling point 1

Key result

Boiling pt.:

>= 276 - <= 280 °C

Atm. press.:

94 kPa

Remarks on result:

other: mean of two tests

Boiling point 2

Boiling pt.:

549 K

Atm. press.:

94 kPa

Any other information on results incl. tables

Table 1. The determination of the Boiling range for the substance T002019 (summary of the capillary test)

Test No	Starting Temperature (deg C)	Heating rate (K/min)	Boiling range (deg C)	Boiling range (K)
1	110	1	277 - 281	550 - 554
2	110	1	275 - 278	548 - 551
Mean boiling point			276 - 280+-2 deg C	549 - 553+-2 K

First bubbles appeared at about 170 deg C and at about 280 deg Ca stream of air bubbles rose from the capillary indicating boiling of the test article. At this temperature the sample turned black under strong foaming. The test article obviously underwent degradation during boiling. The sample color was light brown in the beginning and became black during the test but the liquid sample stayed clear.

Applicant's summary and conclusion

Conclusions:

In conclusion the boiling range for T002019 was determined to be 276 to 280 +/- 2 °C.