Reaction mass of 1,4-bis[(2-ethylhexyl)amino]-9,10-dihydroanthracene-9,10-dione and 1-(butylamino)-4-[(2-ethylhexyl)amino]-9,10-dihydroanthracene-9,10-dione and 1-[(2-ethylhexyl)amino]-4-(methylamino)-9,10-dihydroanthracene-9,10-dione

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

November 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

Commission Regulation (EC) No 440/2008 of 30 May 2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

adopted July 27, 1995

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

column elution method

Key result

Water solubility:

< 0.1 mg/L

Conc. based on:

test mat.

Temp.:

20 °C

pH:

> 7.2 - < 7.6

Results of the determination of Solvent Blue 79 concentrations

Analytical occasion / Time Period	Flow rate (ml / hour)	Measured concentration ofSolvent Blue 79(mg/L)
07 November 2017 / 20 hours	~ 12.5	BQL		pH=7.52
08 November 2017 / 44 hours		BQL		pH=7.45
09 November 2017 / 67 hours		BQL		pH=7.32
10 November 2017 / 90 hours		BQL		pH=7.43
13 November 2017 / 162 hours		BQL		pH =7.48
Mean			BQL
07 November 2017 / 20 hours	~ 25	BQL		pH=7.35
08 November 2017 / 44 hours		BQL		pH=7.39
09 November 2017 / 67 hours		BQL		pH=7.40
10 November 2017 / 90 hours		BQL		pH=7.35
13 November 2017 / 162 hours		BQL		pH=7.40
Mean			BQL
Mean of the two test			BQL

BQL: below of quantitation limit

Conclusions:

The water solubility of Solvent Blue 79 was determined to be less than the quantitation limit (0.1 mg/L after dilution) at 20 °C ± 0.5 °C using the column elution method for the performance of the main test.

Executive summary:

The Column Elution method, according to OECD 105 was used to evaluate the water solubility of Solvent Blue 79. HPLC was used as the method for analysis. Solvent Blue 79 was not detected in any of the analysed solutions, therefore the water solubility can be concluded to be less than the LOQ of the method (0.1mg/L)

Description of key information

The water solubility of Solvent Blue 79 was determined using the column elution method. No Solvent Blue 79 could be detected in any of the test solutions therefore the solubility was determined to be less than the quantitation limit (0.1 mg/L after dilution) at 20 °C ± 0.5 °C.

Key value for chemical safety assessment

Water solubility:

0.1 mg/L

at the temperature of:

20 °C