Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 908-995-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1974
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The test was performed according the internal Guideline of the test institute
- GLP compliance:
- no
- Test organisms (species):
- Leuciscus idus melanotus
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 11 - 12 °dH
- Test temperature:
- 22 °C +/- 0.5
- pH:
- 7.2 - 7.5
- Dissolved oxygen:
- > 7.5 mg/L
- Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 218 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- Mortality in the upper concentrations based on the pH value (high acidity)
- Validity criteria fulfilled:
- yes
- Conclusions:
- The acute toxicity test showed a 48h-LC50 of 218 mg/L.
- Executive summary:
The acute toxicity test showed a 48h-LC50 of 218 mg/L.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1976
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The test was performed according the internal Guideline of the test institute
- GLP compliance:
- no
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- The second species tested was Cyprinus carpio
Salmo gairdneri: 4.5 -12 g, number of fish: 6
Cyprinus carpio: 6.5 - 15 g, number of fish : 6
Depending on the season, the body weight of the fish was so high that in a number of 6 fish per concentration 2 tanks were filled with 3 fish, respectively. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Test temperature:
- Salmo gairdneri: 15 +/- 0.5 °C
Cyprinus carpio: 16 +/- 0.5 °C - pH:
- Salmo gairdneri: 3.25 - 7.55
Cyprinus carpio: 3.1 - 6. 7 - Dissolved oxygen:
- Salmo gairdneri: 7.85 - 9. 15 mg/L
Cyprinus carpio: 7.7 - 8.85 mg/L - Nominal and measured concentrations:
- Samo gairdneri: 0 - 80 - 100 - 125 - 160 - 200 mg/L
Cyprinus carpio: 0 - 100 - 125 - 160 - 200 mg/L - Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 136 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: (salmo gairdneri)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: (salmo gairdneri)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 142 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: (Cyprinus carpio)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 125 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: (Cyprinus carpio)
- Details on results:
- Mortality in the upper concentrations based on the pH value (high acidity)
- Validity criteria fulfilled:
- yes
- Conclusions:
- The acute toxicity test showed a 96h-LC50 of 136 mg/L in salmo gairdneri and 142 mg/L in cyprinus carpio.
- Executive summary:
The acute toxicity test showed a 96h-LC50of 136 mg/Lin salmo gairdneri and 142 mg/L in cyprinus carpio.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1974
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The test was performed according the internal Guideline of the test institute
- GLP compliance:
- no
- Test organisms (species):
- Leuciscus idus melanotus
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 11 - 12 ° dH
- Test temperature:
- 22 °C +/- 0.5
- pH:
- 7.2 - 7.5
- Dissolved oxygen:
- > 7.5 mg/L
- Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- LC0
- Effect conc.:
- 282 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- Mortality in the upper concentrations based on the pH value (high acidity)
- Validity criteria fulfilled:
- yes
- Conclusions:
- The acute toxicity test showed a 48h-LC50 of 282 mg/L
- Executive summary:
The acute toxicity test showed a 48h-LC50 of 282 mg/L
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1976
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The test was performed according the internal Guideline of the test institute
- GLP compliance:
- no
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- The second species tested was Cyprinus carpio
Salmo gairdneri: 2.6 - 12.3 g, number of fish: 6
Cyprinus carpio: 5.1 - 14.9 g, number of fish : 6
Depending on the season, the body weight of the fish was so high that in a number of 6 fish per concentration 2 tanks were filled with 3 fish, respectively. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Test temperature:
- Salmo gairdneri: 15 +/- 0.5 °C
Cyprinus carpio: 16 +/- 0.5 °C - pH:
- Salmo gairdneri: 3.65 - 7.7
Cyprinus carpio: 3.1 - 6. 9 - Dissolved oxygen:
- Salmo gairdneri: 7.8 - 9. 35 mg/L
Cyprinus carpio: 8.2 - 9.45 mg/L - Nominal and measured concentrations:
- Samo gairdneri: 0 - 50 - 80 - 125 - 160 - 200 mg/L
Cyprinus carpio: 0 - 100 - 125 - 160 - 200 mg/L - Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 130 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: (salmo gairdneri)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 80 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: (salmo gairdneri)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 142 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: (Cyprinus carpio)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 125 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: (Cyprinus carpio)
- Details on results:
- Mortality in the upper concentrations based on the pH value (high acidity)
- Validity criteria fulfilled:
- yes
- Conclusions:
- The acute toxicity test showed a 96h-LC50 of 130 mg/L in salmo gairdneri and 142 mg/L in cyprinus carpio.
- Executive summary:
The acute toxicity test showed a 96h-LC50 of 130 mg/Lin salmo gairdneri and 142 mg/L in cyprinus carpio.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- Please refer to chapter 13
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 48 h
- Dose descriptor:
- LC0
- Effect conc.:
- 282 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- Please refer to chapter 13
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 130 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: salmo gairdneri
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 90 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: salmo gairdneri
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 142 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Cyprinus carpio
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 125 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Cyprinus carpio
- Validity criteria fulfilled:
- yes
- Conclusions:
- The acute toxicity test showed a 96h-LC50 of 130 mg/L in salmo gairdneri and 142 mg/L in cyprinus carpio.
- Executive summary:
The acute toxicity test showed a 96h-LC50 of 130 mg/L in salmo gairdneri and 142 mg/L in cyprinus carpio.
Referenceopen allclose all
Description of key information
Four short-term toxicity to fish tests with three different species are available.
The tests with salmo gairdneri shows a 96 h-LC50between 130 and 136 mg/L. The 96 h- LC50on Cyprinus carpio was found to be 142 mg/L. The 48 h LC0on Leuciscus idus was found to be between 218 and 282 mg/L.
All results are above 100 mg/L and therefore it can be concluded that the registered substance is not toxic to fish.
Key value for chemical safety assessment
Additional information
Four short-term toxicity to fish tests with three different species are available. The tests with salmo gairdneri shows a 96 h-LC50between 130 and 136 mg/L. The 96 h- LC50on Cyprinus carpio was found to be 142 mg/L. The 48 h LC0on Leuciscus idus was found to be between 218 and 282 mg/L.
All results are above 100 mg/L and therefore it can be concluded that the registered substance is not toxic to fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.