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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 204-465-2 | CAS number: 121-33-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to soil microorganisms
Administrative data
- Endpoint:
- toxicity to soil microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Test conditions and methods poorly described, semi-quantitative and not validated method.
Data source
Reference
- Reference Type:
- publication
- Title:
- THE DESTRUCTION OF VANILLIN IN THE SOIL BY THE ACTION OF SOIL BACTERIA.
- Author:
- ROBBINS WJ; ELIZANDO AE
- Year:
- 1 918
- Bibliographic source:
- ALA. AGR. EXP. SB. BULL. 204. PP.125-31.
Materials and methods
- Principles of method if other than guideline:
- Amendement of soil with vanillin and soil microorganism quantification.
The effect of vanillin on microorganisms was assessed by measuring the number of microorganisms before and during the incubation period. - GLP compliance:
- no
Test material
- Reference substance name:
- Vanillin
- EC Number:
- 204-465-2
- EC Name:
- Vanillin
- Cas Number:
- 121-33-5
- Molecular formula:
- C8H8O3
- IUPAC Name:
- 1-butoxypropan-2-ol
- Details on test material:
- no data
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test substrate
- Vehicle:
- not specified
Test organisms
- Test organisms (inoculum):
- other: aerobic microorganisms
Study design
- Total exposure duration:
- 57 d
Test conditions
- Details on test conditions:
- The experiment was performed with 2 different soils (Alabama - ALB- and Arlington - ARL- , US). Alabama soil was characterised by the presence of vanillin-destroying bacteria, which were isolated and cultured in mineral media. Arlington soil is a heavy silty clay loam.
An experimental unit was composed by 9 Kg of air dry soil, placed in two-gallon pots and hydrated with distilled water. Each experimental condition was performed in duplicate. The experimental conditions were:
1- ALB
2- ALB + Vanillin [1g/kg]
3- ARL
4- ARL + Vanillin [1g/kg]
5- ARL + Vanillin [1g/kg] + suspension of pure culture of vanillin destroying bacteria
From time to time, the number of microorganisms was determined until 57 days of incubation.
Microorganism concentration determination:
The number of microorganisms was determined by the method described by Brown using albumen agar (no more details were provided by the
authors). The analysis was performed in duplicate using dilution of 1/20000 and 1/200000. - Reference substance (positive control):
- not specified
Results and discussion
- Details on results:
- no data
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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