Registration Dossier
Registration Dossier
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EC number: 221-678-6 | CAS number: 3184-13-2
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09/2017 to 2017-11-06
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 2014
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Version / remarks:
- March 1998
- GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Kyowa Hakko Bio Co. Ltd. / batch 160060
- Expiration date of the lot/batch: 2018-12-01
- Purity test date:2016-12-01
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Ambient temperature (15 °C - 25 °C), protected from light
- Stability under test conditions: stable
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: none - Key result
- Water solubility:
- 455 g/L
- Conc. based on:
- test mat. (total fraction)
- Incubation duration:
- 72 h
- Temp.:
- 30 °C
- Remarks on result:
- completely miscible
- Details on results:
- One preliminary test for the water solubility was carried out. Summarized the solubility of the test item in water was estimated to be 500 g/L.
Based on the guideline the shake flask method has to be used for the test performance for substances with solubility > 10 mg/L. - Conclusions:
- The water solubility was determined to be 455 g/L at 20 °C.
- Executive summary:
The water solubility of L-(+)-2,5-diaminopentanoic acid was determined using the shake flask method. The saturation mass concentrations of the test item were determined using HPLC.
The results showed no tendency to increase, therefore the study is considered to be valid.
Corresponding to the analyses the water solubility was determined to be 455 g/L at 20 °C.
Reference
Description of key information
The water solubility was determined to be 455 g/L at 20 °C.
Key value for chemical safety assessment
- Water solubility:
- 455 g/L
- at the temperature of:
- 20 °C
Additional information
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