Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 226-285-3 | CAS number: 5343-92-0
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable publication which meets basic scientific principles
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- Symrise
- Year:
- 2 003
- Bibliographic source:
- HYDROLITE-5 SURVEY OF SAFETY STUDIES
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- Symrise
- Year:
- 2 005
- Bibliographic source:
- MSDS - 616751 HYDROLITE-5
Materials and methods
- Type of study / information:
- 48 h closed epicutaneous test
- Endpoint addressed:
- skin irritation / corrosion
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Pentane-1,2-diol
- EC Number:
- 226-285-3
- EC Name:
- Pentane-1,2-diol
- Cas Number:
- 5343-92-0
- Molecular formula:
- C5H12O2
- IUPAC Name:
- pentane-1,2-diol
- Details on test material:
- - Name of test material (as cited in study report): Hydrolite-5
Constituent 1
Method
- Details on study design:
- Hydrolite-5 was applied as 10% aqueous solution an the backs of 50 volunteers (30 females and 20 males). 14 of the volunteers had some history of allergy or were skin sensitive and were therefore considered to be specially sensitive. The test sites were assessed immediatly and 24 hours after patch removal.
Results and discussion
- Results:
- No irritant or doubtful reactions could be detected.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
