Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 216-372-4 | CAS number: 1569-01-3
Endpoint summary
Administrative data
Description of key information
Additional information
Three acute toxicity tests including a fish, daphnid and algal study were available for propylene glycol n-propylether (PnP) along with an aerobic biodegradation DOC test following OECD 301A. A 96 -hr acute toxicity study was conducted with rainbow trout (Oncorhynchus mykiss) exposed to propylene glycol n-propyl ether (PnP). This study was consider the key study, was non-GLP and rated a Klimisch score of 2. The 96 -hr LC50 for rainbow trout was > 100 mg/l, the highest concentration tested. A non-GLP acute toxicity study was conducted with the cladoceran, Daphnia magna exposed to propylene glycol n-propyl ether (PnP). This study was considered the key study and was rated a Klimisch score of 2. The 48- hr LC50 with Daphnia magna straus was > 100 mg/l, the highest concentration tested. An acute toxicity test was conducted with the green algae, Selenastrum capricornutum printz (now known asPseudokirchnierella subcapitata) exposed to propylene glycol n-propyl ether (PnP). This study was designated the key study and was rated a Klimisch score of 1. The 72 -hr EC50 value was 3440 mg/L. An aerobic biodegradation DOC die-away test following OECD Method 301A determinded propylene glycol n-propyl ether to be readily biodegradable as >70% of the material was degraded in the first 10 days.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
