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Diss Factsheets
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EC number: 276-602-4 | CAS number: 72363-26-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- Principles of method if other than guideline:
- As per the guideline
- GLP compliance:
- no
- Specific details on test material used for the study:
- FAT 40444/A
- Analytical monitoring:
- not specified
- Details on sampling:
- None
- Vehicle:
- yes
- Details on test solutions:
- Water
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- No. of fish in each group: 7
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
- Test temperature:
- ca. 23 °C
- pH:
- 8.4 - 8.5
- Dissolved oxygen:
- 89 - 97 %
- Nominal and measured concentrations:
- 30, 100 and 300 mg/L
- Reference substance (positive control):
- no
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 300 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- No mortality was observed at concentrations of 30 and 300 mg/L, however, 1 out of 7 fish died when exposed at 100 mg/L concentration.
- Sublethal observations / clinical signs:
LC100 >300 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- 96-h LC50 to fish was determined to be >300 mg/L.
- Executive summary:
The acute toxicity of FAT 40444/A to fish was evaluated in a study conducted according to a methodology equivalent to OECD Guideline 203. Three groups, each containing 7 fish, were exposed to nominal test substance concentrations of 30, 100 and 300 mg/L for 96 h. No mortality was observed at concentrations of 30 and 300 mg/L, however, 1 out of 7 fish died when exposed at 100 mg/L concentration. Hence, the LC50 was determined to be >300 mg/L.
Reference
Description of key information
The acute toxicity of FAT 40444/A to fish was evaluated in a study conducted according to a methodology equivalent to OECD Guideline 203. Three groups, each containing 7 fish, were exposed to nominal test substance concentrations of 30, 100 and 300 mg/L for 96 h. No mortality was observed at concentrations of 30 and 300 mg/L, however 1 out of 7 fish died when exposed at 100 mg/L concentration. Hence, the LC50was determined to be >300 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 300 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.